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NONI

MICROBIAL DEFENSE

FOR:

  • VIRAL INFECTIONS
  • INFLAMMATION
  • IMMUNE SYSTEM MODULATION

General Description

Noni is a tropical fruit that is grown in the Pacific Islands. It has been successfully used for over 2000 years in Polynesia to treat a variety of illnesses. The most beneficial Noni is grown organically in pollution free volcanic soil. James Howenstine, MD, and other medical doctors report that the Nutramedix Noni extract can eliminate the symptoms associated with colds and flu within 3 to 4 hours. Physicians report that 30 ml (one ounce) of Nutramedix Noni extract is as effective as up to 8 liters or 8 quarts of Noni juice from other companies.

Some Reported Medicinal Properties

ADAPTOGEN

ANALGESIC

ANTICANCEROUS

ANTI-INFLAMMATORY

ANTIMICROBIAL

ANTIMUTAGENIC

ANTI-ULCEROUS

IMMUNOMODULATOR

SEDATIVE

Reasearch On Nutramedix Product

in vivo – Anti-inflammatory Effect

Establishment of the Potential Anti-inflammatory Effect of the product known as Noni.  The study demonstrated that Noni had a marked anti-inflammatory effect and was 99% as effective as Feldene, a non-steroidal anti-inflammatory drug also known as PIROXICAM. University of Guayaquil, Department of Chemical Sciences, Guayaquil, Ecuador (2005) Full Article

Establishment of the Potential Anti-inflammatory Effect of the product known as Noni.  The study demonstrated that Noni had a marked anti-inflammatory effect and was 112% as effective as Celebrex, a non-steroidal anti-inflammatory drug also known as PIROXICAM. University of Guayaquil, Department of Chemical Sciences, Guayaquil, Ecuador (2005) Full Article

IN VIvO ACCUTE ORAL TOXICITY TESTS

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Noni did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article

Medical Conditions [peer-reviewed journals]

Cancer

WANG, M. Y., & Su, C. (2001). Cancer preventive effect of Morinda citrifolia (Noni). Annals of the New York Academy of Sciences, 952(1), 161-168. Full Article

Anekpankul, T., Goto, M., Sasaki, M., Pavasant, P., & Shotipruk, A. (2007). Extraction of anti-cancer damnacanthal from roots of Morinda citrifolia by subcritical water. Separation and Purification Technology, 55(3), 343-349. Full Article

Medicinal Properties [peer-reviewed journals]

Antioxidant

Piaru, S. P., Mahmud, R., Abdul Majid, A. M., & Mahmoud Nassar, Z. D. (2012). Antioxidant and antiangiogenic activities of the essential oils of Myristica fragrans and Morinda citrifolia. Asian Pac J Trop Med, 5(4), 294-298. Full Article

Serafini, M. R., Santos, R. C., Guimaraes, A. G., dos Santos, J. P. A., da Conceicao Santos, A. D., Alves, I. A., ... & de Souza Araújo, A. A. (2011). Morinda citrifolia Linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration. Journal of Medicinal Food, 14(10), 1159-1166. Full Article

Masuda, M., Murata, K., Fukuhama, A., Naruto, S., Fujita, T., Uwaya, A., ... & Matsuda, H. (2009). Inhibitory effects of constituents of Morinda citrifolia seeds on elastase and tyrosinase. Journal of Natural Medicines, 63(3), 267-273. Full Article

Ramamoorthy, P. K., & Bono, A. (2007). Antioxidant activity, total phenolic and flavonoid content of Morinda citrifolia fruit extracts from various extraction processes. Journal of Engineering Science and Technology, 2(1), 70-80. Full Article

Yang, J., Paulino, R., Janke-Stedronsky, S., & Abawi, F. (2007). Free-radical-scavenging activity and total phenols of noni (Morinda citrifolia L.) juice and powder in processing and storage. Food Chemistry, 102(1), 302-308. Full Article

Zin, Z. M., Abdul-Hamid, A., & Osman, A. (2002). Antioxidative activities of chromatographic fractions obtained from root, fruit and leaf of Mengkudu (Morinda citrifolia L.) Food Chemistry, 78(2), 227-231. Full Article

Antifungal

Jainkittivong, A., Butsarakamruha, T., & Langlais, R. P. (2009). Antifungal activity of Morinda citrifolia fruit extract against Candida albicans. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 108(3), 394-398. Full Article

Antibacterial

Jayaraman, S. K., Manoharan, M. S., & Illanchezian, S. (2008). Antibacterial, antifungal and tumor cell suppression potential of Morinda citrifolia fruit extracts. International Journal of Integrative Biology, 3(1), 44-49. Full Article

Anti-Tumor

Furusawa, E., Hirazumi, A., Story, S., & Jensen, J. (2003). Antitumour potential of a polysaccharide‐rich substance from the fruit juice of Morinda citrifolia (Noni) on sarcoma 180 ascites tumour in mice. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 17(10), 1158-1164. Full Article

Antiulcer

Muralidharan, P., & Srikanth, J. (2009). Antiulcer activity of Morinda citrifolia Linn fruit extract. J Sci Res, 1(2), 345-352. Full Article

Antimicrobial

Usha, R., Sashidharan, S., & Palaniswamy, M. (2010). Antimicrobial Activity of a Rarely Known Species, Morinda citrifolia L. Ethnobotanical Leaflets, 2010(3), 7. Full Article

Anti-inflammatory

Dussossoy, E., Bichon, F., Bony, E., Portet, K., Brat, P., Vaillant, F., ... & Poucheret, P. (2016). Pulmonary anti-inflammatory effects and spasmolytic properties of Costa Rican noni juice (Morinda citrifolia L.). Journal of Ethnopharmacology, 192, 264-272. Full Article

Basar, S., Uhlenhut, K., Högger, P., Schöne, F., & Westendorf, J. (2010). Analgesic and antiinflammatory activity of Morinda citrifolia L.(Noni) fruit. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 24(1), 38-42. Full Article

Akihisa, T., Matsumoto, K., Tokuda, H., Yasukawa, K., Seino, K. I., Nakamoto, K., ... & Kimura, Y. (2007). Anti-inflammatory and potential cancer chemopreventive constituents of the fruits of Morinda citrifolia (Noni). Journal of Natural Products, 70(5), 754-757. Full Article

Immunomodulating

Palu, A. K., Kim, A. H., West, B. J., Deng, S., Jensen, J., & White, L. (2008). The effects of Morinda citrifolia L.(noni) on the immune system: its molecular mechanisms of action. Journal of Ethnopharmacology, 115(3), 502-506. Full Article

Wound Healing

Nayak, B. S., Sandiford, S., & Maxwell, A. (2009). Evaluation of the wound-healing activity of ethanolic extract of Morinda citrifolia L. leaf. Evidence-Based Complementary and Alternative Medicine, 6(3), 351-356. Full Article

Medicinal Properties
[other journals]

Medical Conditions [other journals]

Videos

Conference Presentations

Patient Reports

“Noni is a very good supplement and helps with immune system.” – M.Z

"I bought this after reading an article about how it can knock out colds and flu within hours. I used it several times when I felt like I was fighting a cold and never got the cold. However, the real test came a few days ago when I was traveling with my 14 and 17-year-old. They both started complaining of bad sore throats and felt like they were getting sick. I pulled out the Noni, (I always know when my kids are actually sick because it is the only time they're willing to take supplements.) Ever skeptical about anything mom gives them, they nonetheless took it and were both amazed when they actually felt better within hours. Great stuff!!" -R.P.

“Really knocks a cold out of your system fast.” – L.A.

“This noni worked Really well preventing me from having gout attacks!” – D.D

"NutraMedix Noni is the best Noni I've ever used. NutraMedix is a small bottle but it actually is a better buy because you don't have to drink it like a shot of liquor like you do with most Noni juices."-A.J.

Dosage Information

15 to 30 drops twice daily (start with 15 drops adding two drops with each dose until you reach 30). May be taken hourly for acute health challenges.

Protocols

Safety Information

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Noni did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article

Product Label

Google Scholar

Search Link
NONI
Noni: Toxicity Test 1

Objectives: To study adverse side effects produced by the administration of Noni Juice Concentrate on body weight and different body systems.

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Noni: Anti-Tumor

An immunomodulatory polysaccharide-rich substance (Noni-ppt) from the fruit juice of Morinda citrifolia has been found to possess both prophylactic and therapeutic potentials against the immunomodulator sensitive Sarcoma 180 tumour system.

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Noni: Antioxidant (chromatographic)

Crude extracts of root, leaf and fruit of Morinda citrifolia were fractionated on a Sephadex LH-20 column with ethanol as eluate.

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Noni: Antioxidant (Free Radical)

Noni (Morinda citrifolia L., Rubiaceae) is a tropical and subtropical plant grown in the Pacific islands and has been used traditionally as a folk medicine to treat a broad range of diseases for over 2000 years.

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Noni: Antioxidant (essential oils)

Essential oils are volatile aromatic oily liquids which are identified by a strong smell and are produced by aromatic plants as secondary metabolites.

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Noni: Wound Healing

Wound healing occurs in three stages: inflammation, proliferation, and remodeling.

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Noni: Pulmonary anti-inflammatory effects and spasmolytic properties noni juice (2015)

Morinda citrifolia L. (Rubiaceae) is a small tropical tree that grows widely in Polynesia.

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Noni: Immunomodulating

Morinda citrifolia L. (noni) from the family Rubiaceae has been used by Polynesians for over 2000 years for two main purposes.

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Noni: Cancer

Morinda citrifolia (Noni) has been extensively used in folk medicine by Polynesians for over 2,000 years.

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Noni: Cancer (Damnacanthal)

Roots of Morinda citrifolia (Noni or Yor in Thai) are the source of important compounds, anthraquinones, which have been proven to have anti-viral, anti-bacterial, anti-cancer activities.

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Noni: Antiulcer

The study was designed to investigate the antiulcer activity of ethyl acetate extract of the fruits of Morinda citrifolia Linn (Rubiaceae) using different models of gastric and duodenal ulceration in rats.

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Noni: Antioxidant Activity (total phenolic)

Soxhlet, Ultrasonic extract of Morinda citrifolia L. fruit and four extracts from high pressure extraction at 10 MPa using ethanol, ethyl acetate as solvent and dried by vacuum oven and spray dryer were analyzed for their antioxidant activity by peroxide value method and diphenylpicrylhydrazyl radical scavenging method.

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Noni: Antimicrobial

Morinda Citrifolia is one of the most important traditional Polynesian medicinal plants.

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Noni: Anti-inflammatory Compared (and cancer)

Morinda citrifolia L. (Rubiaceae), known as “noni”, is a small tree that grows widely across Polynesia.

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Noni: Anti-inflammatory (nociceptive)

Herbal drugs have been used since ancient times to treat a wide range of diseases.

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Noni: Anti-inflammatory (elastase)

A 50% ethanolic extract (MCS-ext) from seeds of Morinda citrifolia (‘‘noni’’ seeds) showed more potent in vitro inhibition of elastase and tyrosinase, and 1,1-diphe-nyl-2-picrylhydrazyl (DPPH) radical scavenging activity than extracts of M. citrifolia leaves or flesh. Activity-gui-ded fractionation of MCS-ext using in vitro assays led to the isolation of ursolic acid as an active constituent of elastase inhibitory activity.

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Noni: Antifungal

The objective of the study was to investigate the antifungal activity of Morinda citrifolia fruit extract on Candida albicans.

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Noni: Antibacterial

Morinda citrifolia (noni) is indigenous to tropical countries and also considered as an important traditional folk medicine. M. citrifolia fruits extracted with three solvents (methanol, ethyl acetate and hexane) were tested in vitro for their antibacterial, antifungal and antitumor activity.

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Noni: Analgesic and Antiinflammatory Activity of Noni (2010

Morinda citrifolia L. is a plant growing in almost all tropical areas of the world.

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