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NONI

MICROBIAL DEFENSE

FOR:

  • VIRAL INFECTIONS
  • INFLAMMATION
  • IMMUNE SYSTEM MODULATION
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General Description

Glucomedix Pitch Deck

Noni is a tropical fruit that is grown in the Pacific Islands. It has been successfully used for over 2000 years in Polynesia to treat a variety of illnesses. The most beneficial Noni is grown organically in pollution free volcanic soil. James Howenstine, MD, and other medical doctors report that the Nutramedix Noni extract can eliminate the symptoms associated with colds and flu within 3 to 4 hours. Physicians report that 30 ml (one ounce) of Nutramedix Noni extract is as effective as up to 8 liters or 8 quarts of Noni juice from other companies.

Some Reported Medicinal Properties

ADAPTOGEN

ANALGESIC

ANTICANCEROUS

ANTI-INFLAMMATORY

ANTIMICROBIAL

ANTIMUTAGENIC

ANTI-ULCEROUS

IMMUNOMODULATOR

SEDATIVE

Research On NutraMedix Product

IN VIVO – ANTI-INFLAMMATORY EFFECT

Establishment of the Potential Anti-inflammatory Effect of the product known as Noni.  The study demonstrated that Noni had a marked anti-inflammatory effect and was 99% as effective as Feldene, a non-steroidal anti-inflammatory drug also known as PIROXICAM. University of Guayaquil, Department of Chemical Sciences, Guayaquil, Ecuador (2005) Full Article

Establishment of the Potential Anti-inflammatory Effect of the product known as Noni.  The study demonstrated that Noni had a marked anti-inflammatory effect and was 112% as effective as Celebrex, a non-steroidal anti-inflammatory drug also known as PIROXICAM. University of Guayaquil, Department of Chemical Sciences, Guayaquil, Ecuador (2005) Full Article

IN VIVO ACUTE ORAL TOXICITY TESTS

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Noni did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article

Medical Conditions [peer-reviewed journals]

CANCER

Brown, A. C. (2012). Anticancer activity of Morinda citrifolia (Noni) fruit: a review. Phytotherapy Research, 26(10), 1427-1440. Full Article

Lv, L., Chen, H., Ho, C. T., & Sang, S. (2011). Chemical components of the roots of Noni (Morinda citrifolia) and their cytotoxic effects. Fitoterapia, 82(4), 704-708. Full Article

Thani, W., Vallisuta, O., Siripong, P., & Ruangwises, N. (2010). Anti-proliferative and antioxidative activities of Thai noni/Yor (Morinda citrifolia Linn.) leaf extract. Southeast Asian J trop med public health, 41(2), 482-.489. Full Article

Wang, M. Y., Peng, L., Lutfiyya, M. N., Henley, E., Weidenbacher-Hoper, V., & Anderson, G. (2009). Morinda citrifolia (noni) reduces cancer risk in current smokers by decreasing aromatic DNA adducts. Nutrition and cancer, 61(5), 634-639. Full Article

Chan-Blanco, Y., Vaillant, F., Perez, A. M., Reynes, M., Brillouet, J. M., & Brat, P. (2006). The noni fruit (Morinda citrifolia L.): A review of agricultural research, nutritional and therapeutic properties. Journal of Food Composition and Analysis, 19(6-7), 645-654. Full Article

Wang, M. Y., & Su, C. (2001). Cancer preventive effect of Morinda citrifolia (Noni). Annals of the New York Academy of Sciences, 952(1), 161-168. Full Article

Anekpankul, T., Goto, M., Sasaki, M., Pavasant, P., & Shotipruk, A. (2007). Extraction of anti-cancer damnacanthal from roots of Morinda citrifolia by subcritical water. Separation and Purification Technology, 55(3), 343-349. Full Article

DIABETES

Lee, S. Y., Park, S. L., Hwang, J. T., Yi, S. H., Nam, Y. D., & Lim, S. I. (2012). Antidiabetic effect of Morinda citrifolia (Noni) fermented by Cheonggukjang in KK-Ay diabetic mice. Evidence-Based Complementary and Alternative Medicine, 2012. Full Article

Medicinal Properties [peer-reviewed journals]

ANTIOXIDANT

Pavithra, S., & Banu, N. (2017). Free Radical Scavenging Activity and Total Antioxidant Capacity of Tin Chlorophyllin from Morinda citrifolia L. Research Journal of Pharmacy and Technology, 10(2), 453-455. Full Article

Krishnaiah, D., Bono, A., Sarbatly, R., & Anisuzzaman, S. M. (2015). Antioxidant activity and total phenolic content of an isolated Morinda citrifolia L. methanolic extract from Poly-ethersulphone (PES) membrane separator. Journal of King Saud University-Engineering Sciences, 27(1), 63-67. Full Article

de Almeida Brito, F., de Oliveira Barreto, E., Serafini, M. R., dos Santos, J. P. A., dos Santos Lima, B., Walker, C. I. B., ... & de Souza Araujo, A. A. (2015). Anti-inflammatory property and redox profile of the leaves extract from Morinda citrifolia L. Journal of Medicinal Plants Research, 9(24), 693-701. Full Article

Piaru, S. P., Mahmud, R., Abdul Majid, A. M., & Mahmoud Nassar, Z. D. (2012). Antioxidant and antiangiogenic activities of the essential oils of Myristica fragrans and Morinda citrifolia. Asian Pac J Trop Med, 5(4), 294-298. Full Article

Serafini, M. R., Santos, R. C., Guimaraes, A. G., dos Santos, J. P. A., da Conceicao Santos, A. D., Alves, I. A., ... & de Souza Araújo, A. A. (2011). Morinda citrifolia Linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration. Journal of Medicinal Food, 14(10), 1159-1166. Full Article

Masuda, M., Murata, K., Fukuhama, A., Naruto, S., Fujita, T., Uwaya, A., ... & Matsuda, H. (2009). Inhibitory effects of constituents of Morinda citrifolia seeds on elastase and tyrosinase. Journal of Natural Medicines, 63(3), 267-273. Full Article

Liu, C. H., Xue, Y. R., Ye, Y. H., Yuan, F. F., Liu, J. Y., & Shuang, J. L. (2007). Extraction and characterization of antioxidant compositions from fermented fruit juice of Morinda citrifolia (Noni). Agricultural Sciences in China, 6(12), 1494-1501. Full Article

Ramamoorthy, P. K., & Bono, A. (2007). Antioxidant activity, total phenolic and flavonoid content of Morinda citrifolia fruit extracts from various extraction processes. Journal of Engineering Science and Technology, 2(1), 70-80. Full Article

Yang, J. I. A. N., Gadi, R. A. M. A., & Thomson, T. A. L. E. N. E. (2011). Antioxidant capacity, total phenols, and ascorbic acid content of noni (Morinda citrifolia) fruits and leaves at various stages of maturity. Micronesica, 41(2), 167-176. Full Article

Yang, J., Paulino, R., Janke-Stedronsky, S., & Abawi, F. (2007). Free-radical-scavenging activity and total phenols of noni (Morinda citrifolia L.) juice and powder in processing and storage. Food Chemistry, 102(1), 302-308. Full Article

Zin, Z. M., Abdul-Hamid, A., & Osman, A. (2002). Antioxidative activities of chromatographic fractions obtained from root, fruit and leaf of Mengkudu (Morinda citrifolia L.) Food Chemistry, 78(2), 227-231. Full Article

ANTIDEPRESSENT

Deng, S., & West, B. J. (2011). Antidepressant effects of noni fruit and its active principals. Asian J Med Sci, 3(2), 79-83. Full Article

ANTIFUNGAL

Jainkittivong, A., Butsarakamruha, T., & Langlais, R. P. (2009). Antifungal activity of Morinda citrifolia fruit extract against Candida albicans. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 108(3), 394-398. Full Article

ANTIBACTERIAL

Silva, A. R. N., Ranaweera, C. B., Karunathilaka, R. N., Pathirana, R., & Ratnasooriya, W. D. (2016). Antibacterial activity of water extracts of different parts of Morinda citrifolia grown in Sri Lanka. Int J Sci Res Publ, 6, 124-7. Full Article

Schäfer, M., Sharp, P., Brooks, V. J., Xu, J., Cai, J., Keuler, N. S., ... & Darien, B. J. (2008). Enhanced bactericidal activity against Escherichia coli in calves fed Morinda citrifolia (Noni) puree. Journal of veterinary internal medicine, 22(2), 499-502. Full Article

Jayaraman, S. K., Manoharan, M. S., & Illanchezian, S. (2008). Antibacterial, antifungal and tumor cell suppression potential of Morinda citrifolia fruit extracts. International Journal of Integrative Biology, 3(1), 44-49. Full Article

De La Cruz-Sánchez, N. G., Gómez-Rivera, A., Alvarez-Fitz, P.,Ventura-Zapata, E., Pérez-García, M. D., Avilés-Flores, M., ... &González-Cortazar, M. (2019). Antibacterial activity of Morinda citrifolia Linneo seeds against Methicillin-Resistant Staphylococcus sppMicrobial pathogenesis128,347-353. Full Article

ANTI-TUMOR

Furusawa, E., Hirazumi, A., Story, S., & Jensen, J. (2003). Antitumour potential of a polysaccharide‐rich substance from the fruit juice of Morinda citrifolia (Noni) on sarcoma 180 ascites tumour in mice. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 17(10), 1158-1164. Full Article

ANTIULCER

Muralidharan, P., & Srikanth, J. (2009). Antiulcer activity of Morinda citrifolia Linn fruit extract. J Sci Res, 1(2), 345-352. Full Article

ANTIMICROBIAL

Usha, R., Sashidharan, S., & Palaniswamy, M. (2010). Antimicrobial Activity of a Rarely Known Species, Morinda citrifolia L. Ethnobotanical Leaflets, 2010(3), 7. Full Article

ANTI-INFLAMMATORY

Sousa, S. G., Oliveira, L. A., de Aguiar Magalhães, D., de Brito, T. V., Batista, J. A., Pereira, C. M. C., ... & da Silva, D. A. (2018). Chemical structure and anti-inflammatory effect of Polysaccharide extracted from Morinda citrifolia Linn (Noni). Carbohydrate Polymers. Full Article

Dussossoy, E., Bichon, F., Bony, E., Portet, K., Brat, P., Vaillant, F., ... & Poucheret, P. (2016). Pulmonary anti-inflammatory effects and spasmolytic properties of Costa Rican noni juice (Morinda citrifolia L.). Journal of Ethnopharmacology, 192, 264-272. Full Article

Huang, H. L., Liu, C. T., Chou, M. C., Ko, C. H., & Wang, C. K. (2015). Noni (Morinda citrifolia L.) fruit extracts improve colon microflora and exert anti-inflammatory activities in Caco-2 cells. Journal of medicinal food, 18(6), 663-676. Full Article

Nitteranon, V., Zhang, G., Darien, B. J., & Parkin, K. (2011). Isolation and synergism of in vitro anti-inflammatory and quinone reductase (QR) inducing agents from the fruits of Morinda citrifolia (noni). Food research international, 44(7), 2271-2277. Full Article

Dussossoy, E., Brat, P., Bony, E., Boudard, F., Poucheret, P., Mertz, C., ... & Michel, A. (2011). Characterization, anti-oxidative and anti-inflammatory effects of Costa Rican noni juice (Morinda citrifolia L.). Journal of ethnopharmacology, 133(1), 108-115. Full Article

Basar, S., Uhlenhut, K., Högger, P., Schöne, F., & Westendorf, J. (2010). Analgesic and antiinflammatory activity of Morinda citrifolia L.(Noni) fruit. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 24(1), 38-42. Full Article

Akihisa, T., Matsumoto, K., Tokuda, H., Yasukawa, K., Seino, K. I., Nakamoto, K., ... & Kimura, Y. (2007). Anti-inflammatory and potential cancer chemopreventive constituents of the fruits of Morinda citrifolia (Noni). Journal of Natural Products, 70(5), 754-757. Full Article

Mckoy, M. G., Thomas, E. A., & Simon, O. R. (2002). Preliminary investigation of the anti-inflammatory properties of an aqueous extract from Morinda citrifolia (Noni). In Proceedings of the Western Pharmacology Society (Vol. 45, pp. 76-78). Seattle, Wash.: The Society. Full Article

ATHLETIC ENDURANCE

Anekpankul, T., Goto, M., Sasaki, M., Pavasant, P., & Shotipruk, A. (2007). Extraction of anti-cancer damnacanthal from roots of Morinda citrifolia by subcritical water. Separation and Purification Technology, 55(3), 343-349. Full Article

HEPATOTOXICITY

Wang, M. Y., Anderson, G., Nowicki, D., & Jensen, J. (2008). Hepatic protection by noni fruit juice against CCl 4-induced chronic liver damage in female SD rats. Plant foods for human nutrition, 63(3), 141-145. Full Article

Stadlbauer, V., Fickert, P., Lackner, C., Schmerlaib, J., Krisper, P., Trauner, M., & Stauber, R. E. (2005). Hepatotoxicity of NONI juice: report of two cases. World journal of gastroenterology: WJG, 11(30), 4758. Full Article

IMMUNOMODULATING

Palu, A. K., Kim, A. H., West, B. J., Deng, S., Jensen, J., & White, L. (2008). The effects of Morinda citrifolia L.(noni) on the immune system: its molecular mechanisms of action. Journal of Ethnopharmacology, 115(3), 502-506. Full Article

Nayak, S., & Mengi, S. (2010). Immunostimulant activity of noni (Morinda citrifolia) on T and B lymphocytes. Pharmaceutical biology, 48(7), 724-731. Full Article

MEMORY IMPROVEMENT

Pachauri, S. D., Tota, S., Khandelwal, K., Verma, P. R. P., Nath, C., Hanif, K., ... & Dwivedi, A. K. (2012). Protective effect of fruits of Morinda citrifolia L. on scopolamine induced memory impairment in mice: a behavioral, biochemical and cerebral blood flow study. Journal of ethnopharmacology, 139(1), 34-41. Full Article

NEURON PROTECTION

Harada, S., Hamabe, W., Kamiya, K., Satake, T., Yamamoto, J., & Tokuyama, S. (2009). Preventive effect of Morinda citrifolia fruit juice on neuronal damage induced by focal ischemia. Biological and Pharmaceutical Bulletin, 32(3), 405-409. Full Article

WOUND HEALING

Nayak, B. S., Sandiford, S., & Maxwell, A. (2009). Evaluation of the wound-healing activity of ethanolic extract of Morinda citrifolia L. leaf. Evidence-Based Complementary and Alternative Medicine, 6(3), 351-356. Full Article

VARIOUS PROPERTIES

Assi, R. A., Darwis, Y., Abdulbaqi, I. M., Vuanghao, L., & Laghari, M. H. (2017). Morinda citrifolia (Noni): A comprehensive review on its industrial uses, pharmacological activities, and clinical trials. Arabian Journal of Chemistry, 10(5), 691-707. Full Article

Singh, D. R. (2012). Morinda citrifolia L.(Noni): A review of the scientific validation for its nutritional and therapeutic properties. Journal of Diabetes and Endocrinology, 3(6), 77-91. Full Article

Medicinal Properties
[other journals]

Medical Conditions [other journals]

Videos

Conference Presentations

Patient Reports

“Noni is a very good supplement and helps with immune system.” – M.Z

"I bought this after reading an article about how it can knock out colds and flu within hours. I used it several times when I felt like I was fighting a cold and never got the cold. However, the real test came a few days ago when I was traveling with my 14 and 17-year-old. They both started complaining of bad sore throats and felt like they were getting sick. I pulled out the Noni, (I always know when my kids are actually sick because it is the only time they're willing to take supplements.) Ever skeptical about anything mom gives them, they nonetheless took it and were both amazed when they actually felt better within hours. Great stuff!!" -R.P.

“Really knocks a cold out of your system fast.” – L.A.

“This noni worked Really well preventing me from having gout attacks!” – D.D

"NutraMedix Noni is the best Noni I've ever used. NutraMedix is a small bottle but it actually is a better buy because you don't have to drink it like a shot of liquor like you do with most Noni juices."-A.J.

Dosage Information

15 to 30 drops twice daily (start with 15 drops adding two drops with each dose until you reach 30). May be taken hourly for acute health challenges.

Protocols

Safety Information

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Noni did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article

Product Label

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Search Link
NONI
Noni: Antibacterial (methicillin) (1)

In traditional medicine, Morinda citrifolia (Noni) is used to treat various ailments, including skin and respiratory tract infections. In this work, a bio-directed study (seed extracts) with five bacteria was carried out against four clinical isolates of Methicillin-Resistant Staphylococcus (MRS) and Staphylococcus aureus ATCC 29213 strain to find molecules capable of inhibiting them.

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Noni: Antioxidant (Fermented)

Extraction and characterization of antioxidative compositions from the extracts of fermented Xisha Noni (Morinda citrifolia L.) juice were studied. The antioxidative constituents of 184.6 g freeze-dried extracts of naturally fermented Xisha Noni juice were isolated successfully by petroleum ether, EtOAc and n-BuOH solvents, and the antioxidative effects were measured according to scavenging activity against hydroxyl generated in Fenton reaction system and superoxide anion radicals in pyrogallol autoxidation system.

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Noni: Various Properties

Morinda citrifolia, commonly called noni, has a long history as a medicinal plant and its use as a botanical dietary supplement has grown tremendously in recent years. This has prompted a concomitant increase in research on the phytochemical constituents and biological activity of noni.

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Noni: Neuron protection

It is known that the fruit juice of Morinda citrifolia (M. citrifolia, Noni, Rubiaceae) has various pharmaco-logical effects such as antioxidant or anti-inflammatory activities, which may help the inhibition of ischemic neu-ronal damage.

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Noni: Memory Improvement

Ethnopharmacological relsevance: Noni (Morinda citrifolia L.) is widely used for different illnesses including CNS disorders. Recently Noni has been reported to prevent amyloid beta induced memory impairment in mice. However, the influence of Noni on cholinergic system has not been explored so far. Therefore, present study was designed to investigate effect of Noni fruit on memory, cerebral blood flow (CBF), oxidative stress and acetylcholinesterase (AChE) activity in scopolamine induced amnesia model.

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Noni: Immunomodulating (T and B)

Morinda citrifolia Linn (Rubiaceae) is a traditional medicinal herb that has been purported to be beneficial in the treatment of infections due to its immune enhancing properties. However, detailed studies highlighting the effect of different compounds isolated from the plant on the immune system are lacking.

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Noni: Hepatotoxicity (Two)

AIM: NONI juice (Morinda citrifolia) is an increasingly popular wellness drink claimed to be beneficial for many illnesses. No overt toxicity has been reported to date. We present two cases of novel hepatotoxicity of NONI juice.

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Noni: Hepatotoxicity (Liver)

Marinda citrifalia (noni) is a tropical plant grown in the South Pacific Islands and has been widely used in folk medicine by the Polynesians for over 2,000 years.

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Noni: Diabetes

Diabetes mellitus (DM) is a chronic disorder characterized by hyperglycemia, with disturbances in carbohydrate, lipid, and lipoprotein metabolism stemming from defects in insulin secretion and insulin action, or both.

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Noni: Cancer (Thai)

Thai people have been using Thai noni or Yor Ban (M. citrifolia Linn.) for up to 10,000 years or more (Spriggs and Ander-son, 1993; Anderson et al, 2006). Thai noni/Yor grows naturally and can be found ev-erywhere in Thailand.

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Noni: Cancer (smokers)

Cigarette smoke is the single known, leading preventable cause of lung cancer. In 2006, an estimated 170,000 cancer deaths in the United States were caused by tobacco smoke. Approximately 45 million Americans are current smokers, of which nearly 11 million, or 24%, are between the ages of 18 and 44.

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Noni: Cancer (Review)

Morinda citrifolia L., the ‘‘noni’’, has been used in traditional Polynesian medicine for over 2000 years. Morinda citrifolia (Rubiaceae) is an evergreen shrub whose ripe fruit has a strong butyric acid smell and flavor.

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Noni: Cancer (cytotoxic)

Roots of Morinda citrifolia (Noni or Yor in Thai) have been used traditionally for thousands of years to treat chronic diseases such as cancer and heart disease. In this study, three new anthraquinones together with 15 known compounds were isolated from the roots of M. citrifolia (Rubiaceae).

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Noni: Cancer (Anti)

This review investigated the relationship of noni juice, or its extract (fruit, leaves or root), to anticancer and/or immunostimulant properties. A Medline search was conducted using the key search words ‘Morinda citrifolia’ and ‘Morinda citrifolia and cancer’ (1964 to October, 2011) along with cross-referencing. Botanical and chemical indexes were not included.

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Noni: Athletic endurance

The ability of noni juice to improve endurance in athletes was evaluated clinically. A placebo-controlled clinical trial with TAHITIAN NONI® Juice (TNJ) was conducted in 40 highly-trained athletes.

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Noni: Antioxidant (maturity)

Abstract—Traditional healers and modern manufacturers both recom-mend noni (Morinda citrifolia) fruits and leaves for good health. We determined antioxidant capacity, total phenols, and ascorbic-acid content of noni fruits and leaves in various stages of maturity.

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Noni: Anti-inflammatory (preliminary)

The fruit juice of Morinda citrifolia (noni, Indian mul-berry, duppy soursop) is commonly used as a "miracle" cure in many tropical countries including Tahiti, Hawaii, and the Caribbean islands.

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Noni: Anti-inflammatory (Isolation)

Morinda citrifolia, commonly called noni, is a plant typically found in the Pacific Islands, Southeast Asia, and other tropical areas. Noni fruits have been used as folk medicine for thousands of years for the alleviation of many diseases including cancer, colds, diabetes, flu, hypertension, and pain (Wang et al., 2002).

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Noni: Anti-inflammatory (colon)

ABSTRACT Intestinal microflora and inflammation are associated with the risk of inflammatory bowel diseases. Noni (Morinda citrifolia L.) has various bioactivities, but its effect on colon health remains unknown.

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Noni: Anti-inflammatory (Characterization)

Morinda citrifolia L. (Rubiaceae) is a small tropical tree that grows widely in Polynesia. Commonly called noni, its fruits have been used as a folk medicine for thousands of years for the treatment of many diseases including diabetes, high blood pressure, inflammation or cancer (Chan-Blanco et al., 2006).

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Noni: Antidepressent

Major depressive disorder, also known as clinical depression, remains a problem among developed and developing nations. Lifetime prevalence estimates range from about 3% of the population (Japan) to 17% (USA), with most nations between 8 and 12% (Andrade et al., 2003).

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Noni: Antibacterial (E.coli)

Background: Although adequate colostrum intake and properly used antibiotics can provide much protection for the bovine neonate, increased antibiotic scrutiny and consumer demand for organic products have prompted investigations of nat-ural immunomodulators for enhancing calf health. One plant-based immunomodulator, Morinda citrifolia (noni) fruit, is a well-recognized natural product that has a broad range of immunomodulatory effects.

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Noni: Various (comprehensive)

This review discusses in details the industrial uses and the pharmacological activities of M. citrifolia fruit,seed, leaf and root, along with their isolated phytochemical compounds, through describing the conducted in vitro and in vivo studies as well as clinical data.

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Noni: Antioxidant (Tin)

The antioxidant activity of tin chlorophyllin from the leaves of Morinda citrifolia L. was investigated by using in vitro antioxidant models such as DPPH scavenging assay andPhosphomolybdenum method. The free radical scavenging activity of tin chlorophyllin on the stable radical 1, 1-diphenyl-2-picrylhydrazyl (DPPH) was evaluated and the percentage of inhibition was determined.

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Noni: Antioxidant (PES)

Antioxidant activity and total phenolic content of an isolated Morinda citrifolia L. methanolic extract by using membrane separator were investigated. The extract of M. citrifolia L. fruitby methanol was separated into permeate and retentate by Poly-ethersulphone (PES).

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Noni: Anti-inflammatory (polysaccharide)

Polysaccharides extracted from plants are very promising molecules in the field of pharmacotherapy. Knowing this, the aim of this study was to extract, characterize and evaluate the action of the polysaccharide of Morinda citrifolia Linn (Noni-PLS) in biological models of inflammatory processes.

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Noni: Antibacterial (Sri lanka)

This study examined the antibacterial potential of water extracts of different parts of Morinda citrifolia (Family: Rubiacae) plants which is used/indicated in Sri Lankan traditional and folk medicine to wash old cutaneous wounds, cuts, abrasion, rashes, bruises or burns, and as a throat gargle.

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Noni: Toxicity Test 1

Objectives: To study adverse side effects produced by the administration of Noni Juice Concentrate on body weight and different body systems.

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Noni: Anti-Tumor

An immunomodulatory polysaccharide-rich substance (Noni-ppt) from the fruit juice of Morinda citrifolia has been found to possess both prophylactic and therapeutic potentials against the immunomodulator sensitive Sarcoma 180 tumour system.

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Noni: Antioxidant (chromatographic)

Crude extracts of root, leaf and fruit of Morinda citrifolia were fractionated on a Sephadex LH-20 column with ethanol as eluate.

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Noni: Antioxidant (Free Radical)

Noni (Morinda citrifolia L., Rubiaceae) is a tropical and subtropical plant grown in the Pacific islands and has been used traditionally as a folk medicine to treat a broad range of diseases for over 2000 years.

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Noni: Antioxidant (essential oils)

Essential oils are volatile aromatic oily liquids which are identified by a strong smell and are produced by aromatic plants as secondary metabolites.

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Noni: Wound Healing

Wound healing occurs in three stages: inflammation, proliferation, and remodeling.

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Noni: Pulmonary anti-inflammatory effects and spasmolytic properties noni juice (2015)

Morinda citrifolia L. (Rubiaceae) is a small tropical tree that grows widely in Polynesia.

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Noni: Immunomodulating

Morinda citrifolia L. (noni) from the family Rubiaceae has been used by Polynesians for over 2000 years for two main purposes.

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Noni: Cancer

Morinda citrifolia (Noni) has been extensively used in folk medicine by Polynesians for over 2,000 years.

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Noni: Cancer (Damnacanthal)

Roots of Morinda citrifolia (Noni or Yor in Thai) are the source of important compounds, anthraquinones, which have been proven to have anti-viral, anti-bacterial, anti-cancer activities.

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Noni: Antiulcer

The study was designed to investigate the antiulcer activity of ethyl acetate extract of the fruits of Morinda citrifolia Linn (Rubiaceae) using different models of gastric and duodenal ulceration in rats.

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Noni: Antioxidant Activity (total phenolic)

Soxhlet, Ultrasonic extract of Morinda citrifolia L. fruit and four extracts from high pressure extraction at 10 MPa using ethanol, ethyl acetate as solvent and dried by vacuum oven and spray dryer were analyzed for their antioxidant activity by peroxide value method and diphenylpicrylhydrazyl radical scavenging method.

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Noni: Antimicrobial

Morinda Citrifolia is one of the most important traditional Polynesian medicinal plants.

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Noni: Anti-inflammatory Compared (and cancer)

Morinda citrifolia L. (Rubiaceae), known as “noni”, is a small tree that grows widely across Polynesia.

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Noni: Anti-inflammatory (nociceptive)

Herbal drugs have been used since ancient times to treat a wide range of diseases.

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Noni: Anti-inflammatory (elastase)

A 50% ethanolic extract (MCS-ext) from seeds of Morinda citrifolia (‘‘noni’’ seeds) showed more potent in vitro inhibition of elastase and tyrosinase, and 1,1-diphe-nyl-2-picrylhydrazyl (DPPH) radical scavenging activity than extracts of M. citrifolia leaves or flesh. Activity-gui-ded fractionation of MCS-ext using in vitro assays led to the isolation of ursolic acid as an active constituent of elastase inhibitory activity.

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Noni: Antifungal

The objective of the study was to investigate the antifungal activity of Morinda citrifolia fruit extract on Candida albicans.

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Noni: Antibacterial

Morinda citrifolia (noni) is indigenous to tropical countries and also considered as an important traditional folk medicine. M. citrifolia fruits extracted with three solvents (methanol, ethyl acetate and hexane) were tested in vitro for their antibacterial, antifungal and antitumor activity.

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Noni: Analgesic and Antiinflammatory Activity of Noni (2010)

Morinda citrifolia L. is a plant growing in almost all tropical areas of the world.

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