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CURCUMIN

AUTOIMMUNE DISORDERS

AUTOIMMUNE DISORDERS - MUSCULOSKELETAL CONDITIONS - MICROBIAL INFECTIONS - INFLAMMATION

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General Description

Glucomedix Pitch Deck

Curcumin contains a highly purified source of curcumin from Curcuma longa using BioSOLVE technology. In addition, no chemical lubricants are used in the encapsulation process and this product contains no diluents, preservatives or binders, thus insuring maximal tolerance and absorption. Curcumin plays a crucial role in resolving issues such as autoimmune disorders, musculoskeletal conditions, microbial infections and inflammation.

Some Reported Medicinal Properties

ANTI-INFLAMMATORY

MUSCULOSKELETAL SUPPORT

Research On NutraMedix Product

Medical Conditions [peer-reviewed journals]

Anti-inflammatory

Ramadan, G., Al-Kahtani, M. A., & El-Sayed, W. M. (2011). Anti-inflammatory and anti-oxidant properties of Curcuma longa (turmeric) versus Zingiber officinale (ginger) rhizomes in rat adjuvant-induced arthritis. Inflammation, 34(4), 291-301. Full Article

Anna, K. T., Suhana, M. E., Das, S., Faizah, O., & Hamzaini, A. H. (2011). Anti-inflammatory effect of Curcuma longa (turmeric) on collagen-induced arthritis: an anatomico-radiological study. Clin Ter, 162(3), 201-207. Full Article

Camacho-Barquero, L., Villegas, I., Sánchez-Calvo, J. M., Talero, E., Sánchez-Fidalgo, S., Motilva, V., & de la Lastra, C. A. (2007). Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and iNOS expression in chronic experimental colitis. International immunopharmacology, 7(3), 333-342. Full Article

Chainani-Wu, N. (2003). Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa). The Journal of Alternative & Complementary Medicine, 9(1), 161-168. Full Article

Gupta, B., & Ghosh, B. (1999). Curcuma longa inhibits TNF-α induced expression of adhesion molecules on human umbilical vein endothelial cells. International journal of immunopharmacology, 21(11), 745-757. Full Article

Gupta, S. K., Agarwal, R., Srivastava, S., Agarwal, P., Agrawal, S. S., Saxena, R., & Galpalli, N. (2008). The anti-inflammatory effects of Curcuma longa and Berberis aristata in endotoxin-induced uveitis in rabbits. Investigative ophthalmology & visual science, 49(9), 4036-4040. Full Article

Musculoskeletal Support

Jiang, X., Wang, S., & Chen, H. (2020). A Novel Fabrication of Dose-Dependent Injectable Curcumin Biocomposite Hydrogel System Anesthetic Delivery Method for Care and Management of Musculoskeletal Pain. Dose-Response, 18(3), 1559325820929555. Full Article

Medicinal Properties [peer-reviewed journals]

Medicinal Properties
[other journals]

Medical Conditions [other journals]

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Patient Reports

Dosage Information

Protocols

Safety Information

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CURCUMIN
Curcumin - Musculoskeletal Support (Pain)

Chronic musculoskeletal pain has biological, psychological, and social components. In this article, we have demonstrated the easily injectable nanocomposite carrier for the treatment of chronic musculoskeletal pain. Briefly, the curcumin (Cur) loaded with lipid nano capsules (LNCs; Cur@LNCs) using the phase invasion method.

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Curcumin - Anti-inflammatory (collagen)

Curcuma longa (CL) or turmeric is an Ayurvedic herb that has been traditionally used to treat inflammatory conditions like rheumatoid arthritis (RA). Collagen-induced arthritis (CIA) is a well established experimental auto-immune mediated polyarthritis in susceptible strains of rodents.

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Curcumin - Anti-inflammatory (TNF)

Identification of non-steroidal anti-inflammatory small molecules is very important for the development of anti-inflammatory drugs. We demonstrate here that out of three compounds, viz diferuloylmethane, p-coumaroylferuloylmethane and di-p-coumaroylmethane, present in the ethyl acetate extract of Curcuma longa, diferuloylmethane is most potent in inhibiting TNF-a induced expression of ICAM-1, VCAM-1 and E-selectin on human umbilical vein endothelial cells.

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Curcumin - Anti-inflammatory (COX-2)

Ulcerative colitis (UC) is a nonspecific inflammatory disorder characterized by oxidative and nitrosative stress, leucocyte infiltration and up-regulation of pro-inflammatory cytokines. Mitogen-activated protein kinases (MAPKs), such as the p38 and the cJun N-terminal kinase (JNK) modulate the transcription of many genes involved in the inflammatory process. Curcumin is a polyphenol derived from Curcuma longa, which is known to have anti-inflammatory activity.

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Curcumin - Anti-inflammatory (Arthritis)

Turmeric (rich in curcuminoids) and ginger (rich in gingerols and shogaols) rhizomes have been widely used as dietary spices and to treat different diseases in Ayurveda/Chinese medicine since antiquity. Here, we compared the anti-inflammatory/anti-oxidant activity of these two plants in rat adjuvant-induced arthritis (AIA).

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Curcumin - Anti-inflammatory (Uveitis)

To investigate the anti-inflammatory effect of topical application of Curcuma longa (C. longa) and Berberis aristata (B. aristata) aqueous extracts on experimental uveitis in the rabbit.

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Curcumin - Anti-inflammatory (safety)

Tumeric is a spice that comes from the root Curcuma longa, a member of the ginger family, Zingaberaceae. In Ayurveda (Indian traditional medicine), tumeric has been used for its medicinal properties for various indications and through different routes of administration, including topically, orally, and by inhalation.

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