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RESVERATROL

ANTIOXIDANT SUPPORT
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General Description

A proprietary blend of Japanese Knotweed (Polygonum cuspidatum) as Trans-resveratrol, and standardized Red Wine (Vitis vinifera) extracts. The stilbene polyphenols found primarily in Knotweed root and grape skins have significant antioxidant properties, and are anticarcinogenic, anti-inflammatory. It also has antidiabetic properties in supporting the action of insulin and has antidiabetic neuropathy effect as well as retinopathy.  

It works against hypertension, cardiovascular disease, and liver injury. It preserves cerebrovascular function by strengthening the epithelium of vascular walls, acting as a protective in the event of ischemic stroke, also protecting the heart muscle.

Resveratrol acts by promoting the recycling ofNAD+ for anti-aging benefits. Moreover, studies have demonstrated that resveratrol activates SIRT I genes, which mimic the healthy aging effects of moderate caloric restriction. It demonstrates antibacterial and antiviral activity whether used alone or with other antimicrobial therapy.

Some Reported Medicinal Properties

ANTIAGING

ANTIBACTERIAL

ANTICARCINOGENIC

ANTIDIABETIC

ANTIINFLAMMATORY

ANTIOXIDANT

ANTIVIRAL

CARDIOVASCULAR SUPPORT

IMMUNE SYSTEM SUPPORT

NEURO PROTECTIVE

Research On NutraMedix Product

Medical Conditions [peer-reviewed journals]

Cancer

Sinha, D., Sarkar, N., Biswas, J., & Bishayee, A.(2016, October). Resveratrol for breast cancer prevention and therapy: Preclinical evidence and molecular mechanisms. In Seminars in cancer biology (Vol. 40, pp.209-232). Academic Press. Full Article

Elshaer, M., Chen, Y., Wang, X. J., & Tang, X.(2018). Resveratrol: An overview of its anti-cancer mechanisms. Life sciences207,340-349. Full Article

Ko, J. H., Sethi, G., Um, J. Y., Shanmugam, M. K., Arfuso, F., Kumar, A. P., ... & Ahn, K. S. (2017). The role of resveratrol in cancer therapy. International journal of molecular sciences18(12),2589. Full Article

Varoni, E. M., Lo Faro, A. F., Sharifi-Rad, J., & Iriti, M. (2016). Anticancer molecular mechanisms of resveratrolFrontiers in nutrition3, 8. Full Article

Cardiovascular Disease

Bonnefont-Rousselot, D. (2016). Resveratrol and cardiovascular diseasesNutrients8(5),250. Full Article

Diabetes

Öztürk, E.,Arslan, A. K. K., Yerer, M. B., & Bishayee, A. (2017). Resveratrol and diabetes: A critical review of clinical studiesBiomedicine & Pharmacotherapy95,230-234. Full Article

Medicinal Properties [peer-reviewed journals]

Antibacterial

Ma, D. S., Tan, L. T. H., Chan, K. G., Yap, W. H., Pusparajah, P., Chuah, L. H., ... & Goh, B. H. (2018). Resveratrol — potential antibacterial agent against food borne pathogensFrontiers in pharmacology9, 102. Full Article

Antioxidant

Oh, W. Y., & Shahidi, F. (2018). Antioxidant activity of resveratrol ester derivatives in food and biological model systems. Food chemistry261,267-273. Full Article

Xia, N., Daiber, A., Förstermann, U., & Li, H.(2017). Antioxidant effects of resveratrol in the cardiovascular system. British journal of pharmacology174(12), 1633-1646. Full Article

Anti-inflammatory

Moussa, C., Hebron, M., Huang, X., Ahn, J., Rissman, R.A., Aisen, P. S., & Turner, R. S. (2017). Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease. Journal of Neuroinflammation, 14(1), 1. Full Article

Medicinal Properties
[other journals]

Medical Conditions [other journals]

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Dosage Information

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Product Label

Reveratrol: Diabetes (critical)

Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia. The disease results from the defects of insulin secretion and/or action. Resveratrol is a non-flavonoid polyphenol that naturally occurs as phytoalexin.

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Reveratrol: Cardiovascular (diseases)

The increased incidence of cardiovascular diseases (CVDs) has stimulated research for substances that could improve cardiovascular health. Among them, resveratrol (RES), a polyphenolic compound notably present in grapes and red wine, has been involved in the “French paradox”.

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Reveratrol: Cancer (Role)

Natural product compounds have recently attracted significant attention from the scientific community for their potent effects against inflammation-driven diseases, including cancer. A significant amount of research, including preclinical, clinical, and epidemiological studies, has indicated that dietary consumption of polyphenols, found at high levels in cereals, pulses, vegetables, and fruits, may prevent the evolution of an array of diseases, including cancer.

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Reveratrol: Cancer (preclinical)

Globally, breast cancer is the most frequently diagnosed cancer among women. The major unresolved problems with metastatic breast cancer is recurrence after receiving objective response to chemotherapy, drug-induced side effects of first line chemotherapy and delayed response to second line of treatment.

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Reveratrol: Cancer (overview)

Cancer is one of the leading causes of death worldwide. Chemotherapy and radiotherapy are the conventional primary treatments for cancer patients. However, most of cancer cells develop resistance to both chemotherapy and radiotherapy after a period of treatment, besides their lethal side-effects.

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Reveratrol: Cancer (Molecular)

Resveratrol is a pleiotropic phytochemical belonging to the stilbene family. Though it is only significantly present in grape products, a huge amount of preclinical studies investigated its anticancer properties in a plethora of cellular and animal models

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Reveratrol: Antioxidant (ester)

The antioxidant effects of resveratrol (3,5,4’-trihydroxy-trans-stilbene) contribute substantially to the health benefits of this compound. Resveratrol has been shown to be a scavenger of a number of free radicals. However, the direct scavenging activities of resveratrol are relatively poor.

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Reveratrol: Antioxidant (cardiovascular)

The antioxidant effects of resveratrol (3,5,4’-trihydroxy-trans-stilbene) contribute substantially to the health benefits of this compound. Resveratrol has been shown to be a scavenger of a number of free radicals. However, the direct scavenging activities of resveratrol are relatively poor.

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Reveratrol: Antiinflammatory (adaptive)

Treatment of mild-moderate Alzheimer’s disease (AD) subjects (N = 119) for 52 weeks with the SIRT1 activator resveratrol (up to 1 g by mouth twice daily) attenuates progressive declines in CSF Aβ40 levels and activities of daily living (ADL) scores.

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Reveratrol: Antibacterial (foodborne)

Bacterial foodborne pathogens are a significant health burden and the recent emergence of pathogenic resistant strains due to the excessive use of antibiotics makes it more difficult to effectively treat infections as a result of contaminated food. Awareness of this impending health crisis has spurred the search for alternative antimicrobials with natural plant antimicrobials being among the more promising candidates as these substances have good acceptability and likely low toxicity levels as they have long been used in traditional medicines.

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