DANDELION

DIURETIC

DETOXIFYING

ANTIOXIDANT

ANTI-INFLAMMATORY

HEPATOPROTECTIVE

DIGESTIVE

CHOLERETIC

NUTRITIVE  

IMMUNOMODULATORY

MILD LAXATIVE

ANTIMICROBIAL

ANTIRHEUMATIC

HYPOGLYCEMIC

CARDIOPROTECTIVE

Antioxidant Properties

Aremu, O. O., Oyedeji, A. O., Oyedeji, O. O., Nkeh-Chungag, B. N., & Sewani Rusike, C. R. (2019). In vitro and in vivo antioxidant properties of Taraxacum officinale in Nω-nitro-l-arginine methyl ester (L-NAME)-induced hypertensive rats. Antioxidants, 8(8), 309. Full Article

Colle, D., Arantes, L. P., Gubert, P., da Luz, S. C. A., Athayde, M. L., Rocha, J. B. T., & Soares, F. A. A. (2012). Antioxidant properties of Taraxacum officinale leaf extract are involved in the protective effect against hepatotoxicity induced by acetaminophen in mice. Journal of Medicinal Food, 15(6), 549–556. Full Article

Esatbeyoglu, T., et al. (2016). Sesquiterpene lactone composition and cellular Nrf2 induction of Taraxacum officinale leaves and roots and taraxinic acid β-D-glucopyranosyl ester. Journal of Medicinal Food, 19(12), 1195–1203. Full Article

García-Carrasco, B., Fernandez-Dacosta, R., Dávalos, A., Ordovás, J. M., & Rodriguez-Casado, A. (2015). In vitro hypolipidemic and antioxidant effects of leaf and root extracts of Taraxacum officinale. Medical Sciences, 3(2), 38–54. Full Article

Huang, S., Meng, N., Liu, Z., Guo, L., Dong, L., Li, B., & Ye, Q. (2018). Neuroprotective effects of Taraxacum officinale Wigg. extract on glutamate-induced oxidative stress in HT22 cells via HO-1/Nrf2 pathways. Nutrients, 10(7), 926. Full Article

Jędrejek, D., Kontek, B., Lis, B., Stochmal, A., & Olas, B. (2017). Evaluation of antioxidant activity of phenolic fractions from the leaves and petals of dandelion in human plasma treated with H₂O₂ and H₂O₂/Fe. Chemico-Biological Interactions, 262, 29–37. Full Article

Majewski, M., Lis, B., Juśkiewicz, J., Ognik, K., Borkowska-Sztachańska, M., Jędrejek, D., Stochmal, A., & Olas, B. (2020). Phenolic fractions from dandelion leaves and petals as modulators of the antioxidant status and lipid profile in an in vivo study. Antioxidants, 9(2), 131. Full Article

Park, C. M., Cho, C. W., & Song, Y. S. (2014). TOP 1 and 2, polysaccharides from Taraxacum officinale, inhibit NFκB-mediated inflammation and accelerate Nrf2-induced antioxidative potential through modulation of PI3K-Akt signaling in RAW 264.7 cells. Food and Chemical Toxicology, 66, 56–64. Full Article

Ren, Y. S., Zheng, Y., Duan, H., Lei, L., Deng, X., Liu, X. Q., Mei, Z. N., & Deng, X. K. (2020). Dandelion polyphenols protect against acetaminophen-induced hepatotoxicity in mice via activation of the Nrf-2/HO-1 pathway and inhibition of the JNK signaling pathway. Chinese Journal of Natural Medicines, 18(2), 103–113. Full Article

Sun, Y., Wu, Y., Wang, Z., Chen, J., Yang, Y., & Dong, G. (2020). Dandelion extract alleviated lipopolysaccharide-induced oxidative stress through the Nrf2 pathway in bovine mammary epithelial cells. Toxins, 12(8), 496. Full Article

Yoon, H. S., & Park, C. M. (2019). Alleviated oxidative damage by Taraxacum officinale through the induction of Nrf2-MAPK/PI3K mediated HO-1 activation in murine macrophages RAW 264.7 cell line. Biomolecules, 9(7), 288. Full Article

Anti-inflammatory Properties

Davaatseren, M., et al. (2013). Dandelion leaf extract protects against liver injury induced by methionine- and choline-deficient diet in mice. Journal of Medicinal Food, 16(1), 26–33. Full Article

Dong, L., et al. (2020). Taraxacum officinale Wigg. attenuates inflammatory responses in murine microglia through the Nrf2/HO-1 and NF-κB signaling pathways. The American Journal of Chinese Medicine, 48(2), 445–462. Full Article

Hu, G., et al. (2017). Effects of aqueous extracts of Taraxacum officinale on expression of TNF-alpha and ICAM-1 in LPS-stimulated RMMVECs. BMC Complementary and Alternative Medicine, 17, 38. Full Article

Jeon, D., Kim, S. J., & Kim, H. S. (2017). Anti-inflammatory evaluation of the methanolic extract of Taraxacum officinale in LPS-stimulated human umbilical vein endothelial cells. BMC Complementary and Alternative Medicine, 17, 508. Full Article

Antidepressant / Neurological Effects

Gao, C., et al. (2019). Antidepressive effects of Taraxacum officinale in a mouse model of depression. Medical Science Monitor, 25, 389–394. Full Article

Li, Y. C., et al. (2014). Antidepressant effects of the water extract from Taraxacum officinale leaves and roots in mice. Pharmaceutical Biology, 52(8), 1028–1032. Full Article

Antiviral Properties

Flores-Ocelotl, M. R., et al. (2018). Taraxacum officinale and Urtica dioica extracts inhibit dengue virus serotype 2 replication in vitro. BMC Complementary and Alternative Medicine, 18, 95. Full Article

Antidiabetic Properties

Choi, J., Yoon, K. D., & Kim, J. (2018). Chemical constituents from Taraxacum officinale and their α-glucosidase inhibitory activities. Bioorganic & Medicinal Chemistry Letters, 28(3), 476–481. Full Article

Wirngo, F. E., Lambert, M. N., & Jeppesen, P. B. (2016). The physiological effects of dandelion (Taraxacum officinale) in type 2 diabetes. The Review of Diabetic Studies, 13(2-3), 113–131. Full Article

Hepatoprotective Properties

Gulfraz, M., et al. (2014). Effect of leaf extracts of Taraxacum officinale on CCl₄ induced hepatotoxicity in rats. Pakistan Journal of Pharmaceutical Sciences, 27(4), 825–829. PMID: 25015447

Hfaiedh, M., Brahmi, D., & Zourgui, L. (2016). Hepatoprotective effect of Taraxacum officinale leaf extract on sodium dichromate-induced liver injury in rats. Environmental Toxicology, 31(3), 339–349. Full Article

Antibacterial Properties

Qian, L., et al. (2014). Preparation and antibacterial activity of oligosaccharides derived from dandelion. International Journal of Biological Macromolecules, 64, 392–394. Full Article

Cardiovascular Support

Olas, B. (2022). New perspectives on the effect of dandelion, its food products and other preparations on the cardiovascular system and its diseases. Nutrients, 14(7), 1350. Full Article

Phytochemical Composition

Schütz, K., et al. (2004). Characterization of phenolic acids and flavonoids in dandelion by HPLC/ESI-MS. Rapid Communications in Mass Spectrometry, 19(2), 179–186. Full Article

Williams, C. A., et al. (1996). Flavonoids, cinnamic acids and coumarins from different tissues of Taraxacum officinale. Phytochemistry, 42(1), 121–127. Full Article

Wang, L., et al. (2019). Ultrasonic-assisted enzymatic extraction and characterization of polysaccharides from dandelion leaves. International Journal of Biological Macromolecules, 126, 846–856. Full Article

Antimicrobial / Antibiofilm Activity

Sharifi-Rad, M., et al. (2018). Ethnobotany of the genus Taraxacum—Phytochemicals and antimicrobial activity. Phytotherapy Research, 32(11), 2131–2145. Full Article

Xu, P., et al. (2021). Antibiofilm activity against Staphylococcus aureus and content analysis of Taraxacum officinale phenolic extract. Polish Journal of Veterinary Sciences, 24(2), 243–251. Full Article

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Put 30 drops in 4 oz (120 mL) of water and wait one minute before drinking. May be taken 2-3 times per day or as directed by your physician