UP
FOR RESOLVING AUTOIMMUNE DISORDERS, SUPPRESSED IMMUNE SYSTEM, MICROBIAL INFECTIONS, INFLAMMATION, ETC
Baikal skullcap (Scutellaria baicalensis) is a perennial flowering plant native to East Asia, particularly China, Korea, Mongolia, and parts of Russia. It has been a staple in traditional Chinese medicine (TCM) for over 2,000 years, commonly known as “Huang Qin” . Baikal skullcap has a distinct history of being used to clear heat, dry dampness, and detoxify the body—functions aligned with traditional Eastern medical philosophies.
One of the most notable attributes of Baikal skullcap is its hepatoprotective capacity. It has been shown to reduce liver inflammation and damage in models of chemical-induced liver injury, and also to modulate the gut-liver axis in metabolic disorders. Additionally, it has demonstrated neuroprotective effects in preclinical studies, with potential applications in conditions such as Alzheimer’s and Parkinson’s diseases.
HEPATOPROTECTIVE
ANTI-INFLAMMATORY
ANTIOXIDANT
NEUROPROTECTIVE
ANTIVIRAL
ANTIBACTERIAL / ANTIMICROBIAL
ANTICANCER / ANTITUMOR
CARDIOPROTECTIVE
ANTI-DIABETIC / GLUCOSE REGULATING
LIPID-LOWERING / HYPOLIPIDEMIC
ANTI-ALLERGIC / ANTI-ECZEMA
DETOXIFICATION SUPPORT
MODULATION OF CYTOCHROME P450 ENZYMES
Puri, A., et al. (2019). Antitumor properties of Scutellaria baicalensis extracts in in vitro and in vivo cancer models. Phytomedicine, 58, 152877.
Wang, X., et al. (2018). Apoptosis-inducing effects of baicalein in cancer cells: A systematic review. Biomedicine & Pharmacotherapy, 108, 1103–1112.
Ahmadi, A., et al. (2022). Scutellaria baicalensis and its major flavonoids for liver protection: A review of mechanisms and effects. Journal of Ethnopharmacology.
Wen, Y., Wang, Y., Zhao, C., et al. (2023). Baicalin ameliorates liver injury and metabolic disorder through the gut-liver axis. Frontiers in Pharmacology.
Li, H., et al. (2011). Pharmacological effects and pharmacokinetics properties of baicalin: A comprehensive review. Current Drug Metabolism.
Regulska-Ilow, B., et al. (2004). Influence of bioflavonoids from the radix extract of Scutellaria baicalensis on serum lipids and development in rats. Nahrung/Food, 48(2), 123–128. Full Article
Cytochrome P450 / Herb-Drug Interactions
Yi, S., et al. (2009). Effects of Scutellariae radix and other herbs on cytochrome P450 activities in healthy volunteers. Basic & Clinical Pharmacology & Toxicology, 105, 249–256. Full Article
Chmiel, M., et al. (2023). Anti-neuroinflammatory properties of flavonoids from Scutellaria baicalensis in Alzheimer's disease models. Molecules.
Dmitrieva, A., & Kozlova, O. (2023). Neuroprotective effects of baicalein: Implications for neurodegenerative disorders. International Journal of Molecular Sciences.
Arweiler, N. B., et al. (2011). Influence of Scutellaria baicalensis extract on the initial oral biofilm in humans. Archives of Oral Biology, 56(7), 728–732.
Hong, Y. S., et al. (2013). Antibacterial effect of Scutellaria baicalensis against oral pathogens. Journal of Periodontal & Implant Science, 43(2), 72–78.
Adam, J., et al. (2020). Facial eczema triggered by sunscreen: A novel reaction involving herbal extract ingredients. Contact Dermatitis, 83(6), 460–462.
Huang, M., et al. (2023). Systematic review of pharmacokinetics of baicalin and baicalein in humans and animals. Frontiers in Pharmacology.
Zhao, Q., et al. (2019). Scutellaria baicalensis: A review of its traditional uses, phytochemistry, and pharmacology. Biomedicine & Pharmacotherapy, 117, 109078.
Put 2 to 60 drops in 4 oz (120 mL) of water and wait one minute before drinking. Start with 2 drops (30 min before meals) increasing by 2 drops with each dose up to 60 drops, 2 times a day or as directed by physician
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