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VITAMIN C

DIETARY SUPPLEMENT

FOR RESOLVING ISSUES RELATED TO OXIDATIVE STRESS IN THE BODY

General Description

Vitamin C – Dietary Supplement contains a highly purified source of ascorbic acid and is comparable to reagent grade vitamin C.  This hypo-allergenic form is made from tapioca instead of corn – having absolutely no traces of corn antigen or other allergenic materials – so that those individuals with food sensitivities who are not able to tolerate other, less pure forms of ascorbic acid can benefit.  In addition, no chemical lubricants are used in the encapsulation process and this product contains no diluents, preservatives or binders, thus insuring maximal tolerance and absorption.  Vitamin C plays a critical role in your body.  It is a powerful antioxidant, aids in wound healing, stimulates white blood cell immune activity and helps the body combat colds, flu and other infections.  It also supports cardiovascular health and aids in iron absorption.  Vitamin C deficiency can be a real problem and is not uncommon when undergoing emotional stress or higher levels of physical stress such as burns, surgery, or other trauma.  It is very beneficial when dealing with other ailments such as allergies and infections.

Some Reported Medicinal Properties

ANTI-ANEMIC

ANTI-CANCER

ANTI-CARDIOVASCULAR DISEASE

ANTI-CATARACT

ANTI-CONTUSION

ANTI-EPISTAXIS

ANTI-GINGIVITIS

ANTI-HYPERKERATOSIS

ANTIHYPERTENSIVE

ANTI-INFLAMMATORY

ANTI-METHEMOGLOBINEMIC

ANTIOXODANT

ANTI-SCLEROTIC

ANTI-SCURVY

ANTIVIRAL

COLLAGEN SYNTHESIZER

FORMS HEALTHY SCARS

HEALS WOUNDS

Reasearch On Nutramedix Product

One to two capsules per day after a meal or as directed by your physician.  For patients with a Vitamin C deficiency and/or constipation (less than 3 bowel movements per day), add 1 capsule per day over 2 doses (morning and evening) until bowel tolerance (the dose tolerated by a patient without producing diarrhea) is reached. Some patients require up to 12 capsules per day (6 in the morning and 6 in the evening) to reach bowel tolerance. Hemolysis is possible when taking vitamin C of any type in patients with a G6PD deficiency and should be monitored.

Medical Conditions [peer-reviewed journals]

AIDS

Cathcart III, R. F. (1984). Vitamin C in the treatment of acquired immune deficiency syndrome (AIDS). Medical Hypotheses, 14(4), 423-433. Full Article

Arteriosclerosis

Salonen, R. M., Nyyssonen, K., Kaikkonen, J., Porkkala-Sarataho, E., Voutilainen, S., Rissanen, T. H., ... & Vanharanta, M. (2003). Six-year effect of combined vitamin C and E supplementation on atherosclerotic progression: the Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) Study. Circulation, 107(7), 947-953. Full Article

Huang, H. Y., Appel, L. J., Croft, K. D., Miller III, E. R., Mori, T. A., & Puddey, I. B. (2002). Effects of vitamin C and vitamin E on in vivo lipid peroxidation: results of a randomized controlled trial. The American journal of clinical nutrition, 76(3), 549-555. Full Article

Cancer

Padayatty, S. J., Riordan, H. D., Hewitt, S. M., Katz, A., Hoffer, L. J., & Levine, M. (2006). Intravenously administered vitamin C as cancer therapy: three cases. Canadian Medical Association Journal, 174(7), 937-942. Full Article

Common Cold

Douglas, R. M., & Hemilä, H. (2005). Vitamin C for preventing and treating the common cold. PLoS medicine, 2(6), e168. Full Article

Diabetes

Afkhami-Ardekani, M., & Shojaoddiny-Ardekani, A. (2007). Effect of vitamin C on blood glucose, serum lipids & serum insulin in type 2 diabetes patients. Indian Journal of Medical Research, 126(5), 471. Full Article

Obstructive sleep apnea (OSA)

Grebe, M., Eisele, H. J., Weissmann, N., Schaefer, C., Tillmanns, H., Seeger, W., & Schulz, R. (2006). Antioxidant vitamin C improves endothelial function in obstructive sleep apnea. American journal of respiratory and critical care medicine, 173(8), 897-901. Full Article

Pressure ulcers

Desneves, K. J., Todorovic, B. E., Cassar, A., & Crowe, T. C. (2005). Treatment with supplementary arginine, vitamin C and zinc in patients with pressure ulcers: a randomised controlled trial. Clinical nutrition, 24(6), 979-987. Full Article

Various Conditions

Li, Y., & Schellhorn, H. E. (2007). New developments and novel therapeutic perspectives for vitamin C. The Journal of nutrition, 137(10), 2171-2184. Full Article

Jacob, R. A., & Sotoudeh, G. (2002). Vitamin C function and status in chronic disease. Nutrition in clinical care, 5(2), 66-74. Full Article

Medicinal Properties [peer-reviewed journals]

Antioxidant

Sreeramulu, D., & Raghunath, M. (2010). Antioxidant activity and phenolic content of roots, tubers and vegetables commonly consumed in India. Food Research International, 43(4), 1017-1020. Full Article

Wong, S. P., Leong, L. P., & Koh, J. H. W. (2006). Antioxidant activities of aqueous extracts of selected plants. Food chemistry, 99(4), 775-783. Full Article

Padayatty, S. J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J. H., ... & Levine, M. (2003). Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American college of Nutrition, 22(1), 18-35. Full Article

Rahmat, A., Kumar, V., Fong, L. M., Endrini, S., & Sani, H. A. (2003). Determination of total antioxidant activity in three types of local vegetables shoots and the cytotoxic effect of their ethanolic extracts against different cancer cell lines. Asia Pacific journal of clinical nutrition, 12(3), 292-295. Full Article

Kim, D. O., Lee, K. W., Lee, H. J., & Lee, C. Y. (2002). Vitamin C equivalent antioxidant capacity (VCEAC) of phenolic phytochemicals. Journal of Agricultural and food chemistry, 50(13), 3713-3717. Full Article

Bowie, A. G., & O’Neill, L. A. (2000). Vitamin C inhibits NF-κB activation by TNF via the activation of p38 mitogen-activated protein kinase. The Journal of Immunology, 165(12), 7180-7188. Full Article

Gardner, P. T., White, T. A., McPhail, D. B., & Duthie, G. G. (2000). The relative contributions of vitamin C, carotenoids and phenolics to the antioxidant potential of fruit juices. Food chemistry, 68(4), 471-474. Full Article

Podmore, I. D., Griffiths, H. R., Herbert, K. E., Mistry, N., Mistry, P., & Lunec, J. (1998). Vitamin C exhibits pro-oxidant properties. Nature, 392(6676), 559. Full Article

Anti-inflammatory

Harrison, S. A., Torgerson, S., Hayashi, P., Ward, J., & Schenker, S. (2003). Vitamin E and vitamin C treatment improves fibrosis in patients with nonalcoholic steatohepatitis. The American journal of gastroenterology, 98(11), 2485-2490. Full Article

Brain Function

Harrison, F. E., & May, J. M. (2009). Vitamin C function in the brain: vital role of the ascorbate transporter SVCT2. Free Radical Biology and Medicine, 46(6), 719-730. Full Article

Chemoprotective

ANTUNES, L. M. G., DARIN, J. D. A. C., & BIANCHI, M. D. L. P. (2000). Protective effects of vitamin C against cisplatin-induced nephrotoxicity and lipid peroxidation in adult rats: a dose-dependent study. Pharmacological Research, 41(4), 405-411. Full Article

Coronary Health

Osganian, S. K., Stampfer, M. J., Rimm, E., Spiegelman, D., Hu, F. B., Manson, J. E., & Willett, W. C. (2003). Vitamin C and risk of coronary heart disease in women. Journal of the American College of Cardiology, 42(2), 246-252. Full Article

Kaufmann, P. A., Gnecchi-Ruscone, T., Di Terlizzi, M., Schäfers, K. P., Lüscher, T. F., & Camici, P. G. (2000). Coronary heart disease in smokers: vitamin C restores coronary microcirculatory function. Circulation, 102(11), 1233-1238. Full Article

Immunomodulating

Wintergerst, E. S., Maggini, S., & Hornig, D. H. (2006). Immune-enhancing role of vitamin C and zinc and effect on clinical conditions. Annals of Nutrition and Metabolism, 50(2), 85-94. Full Article

Wound Healing

Erazo-Pagador, G., & Din, M. S. (2001). Rapid wound healing in African catfish, Clarias gariepinus, fed diets supplemented with ascorbic acid. Full Article

Medicinal Properties
[other journals]

Medical Conditions [other journals]

Videos

Conference Presentations

Patient Reports

“My daughter and husband came home with nasty colds – sniffling, sneezing, runny noses, the whole bit.  I gave each of them Nutramedix Vitamin C and they woke up feeling right as rain!  (I was nervous since they’ve had reactions to other Vitamin C products.)  This stuff is miraculous!” -R.I.

“I’m highly sensitive to corn derivatives. Thrilled to finally find a safe Vitamin C! Definitely has improved my energy levels and immune system.” – A.B

“As a smoker, I pretty much always feel drained.  I came down with absolutely everything that was going around.  When I used a sample of this vitamin C, I had more energy and got through my day.”-N.L.

Dosage Information

One to two capsules per day after a meal or as directed by your physician.  For patients with a Vitamin C deficiency and/or constipation (less than 3 bowel movements per day), add 1 capsule per day over 2 doses (morning and evening) until bowel tolerance (the dose tolerated by a patient without producing diarrhea) is reached. Some patients require up to 12 capsules per day (6 in the morning and 6 in the evening) to reach bowel tolerance.  Hemolysis is possible when taking vitamin C of any type in patients with a G6PD deficiency and should be monitored.

Protocols

Safety Information

Product Label

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VITAMIN C
Vitamin C: Wound Healing

Wound healing in African catfish, Clarias gariepinus, fed diets supplemented with ascorbic acid was studied under laboratory conditions.s

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Vitamin C: various conditions

Vitamin C is an essential dietary nutrient required as a co-factor for many enzymes, and humans are among the few animals that lack the ability to synthesize the compound from glucose.

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Vitamin C: various conditions (New Dev)

Vitamin C is required for collagen synthesis and biosynthesis of certain hormones and recommended dietary intake levels are largely based these requirements.

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Vitamin C: pressure ulcers

Pressure ulcers are areas of damage to the skin and underlying tissue that usually occur over bony protrusions such as elbows, heels and hips.

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Vitamin C: Obstructive sleep apnea (OSA)

Obstructive sleep apnea (OSA) is associated with oxidative stress, endothelial dysfunction, and increased cardiovascular morbidity and mortality.

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Vitamin C: immunomodulating

Vitamin C concentrations in the plasma and leukocytes rapidly decline during infections and stress.

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Vitamin C: Diabetes

Vitamin C is an important antioxidant in human, capable of scavenging oxygen-derived free radicals.

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Vitamin C: Cornoary Health

Cigarette smoking is a well established risk factor for cardiovascular disease, and it affects both the coronary and the peripheral circulation.

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Vitamin C: Cornoary Health (Women)

Vitamin C is the main water-soluble antioxidant in human plasma and is hypothesized to have a protective role in the development of atherosclerotic heart disease by inhibiting low-density lipoprotein oxidation.

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Vitamin C: Common Cold

The role of vitamin C in the prevention and treatment of the common cold has been a subject of controversy for at least 60 years.

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Vitamin C: Common Cold (double-blind)

A large scale double-blind trial was conducted to test the claim that the intake of one gram of vitamin C per day substantially reduces the frequency and duration of "colds".

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Vitamin C: chemoprotective

Cisplatin (cis-diamminedichloroplatinum II) is one of the most potent chemotherapeutic antitumor drugs.

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Vitamin C: Cancer

Early clinical studies showed that high-dose vitamin C, given by intravenous and oral routes, may improve symptoms and prolong life in patients with terminal cancer.

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Vitamin C: Brain Function

Ascorbate (vitamin C) is a vital antioxidant molecule in the brain.

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Vitamin C: arteriosclerosis

Multidisciplinary evidence indicates that enhanced lipid peroxidation is associated with accelerated atherogenesis and that self-selected use of antioxidant supplements is associated with reduced atherosclerosis.

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Vitamin C: arteriosclerosis (peroxidation)

Lipid peroxidation may be important in the pathogenesis of atherosclerotic cardiovascular disease, particularly in its earliest stages.

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Vitamin C: Anti-inflammatory (fibrosis)

Nonalcoholic steatohepatitis (NASH) is one of the most common forms of liver disease and is frequently associated with clinical conditions such as obesity, type II diabetes mellitus, hyperlipidemia, and hypertension.

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Vitamin C: Anioxidant

The presence of free radicals in the body causes cell and tissue damage.

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Vitamin C: Anioxidant (roots)

Excess free radical production underlies the pathogenesis of diseases like atherosclerosis, carcinogenesis, diabetes, cataract and accelerated ageing.

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Vitamin C: Anioxidant (Pro-oxi)

Vitamin C is marketed as a dietary supplement, partly because of its ‘antioxidant’ properties.

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Vitamin C: Anioxidant (NF-kB)

Vitamin C (ascorbic acid) is required in the diets of humans and several other species that lack the terminal enzyme in its synthetic pathway, L-gulonolactone oxidase.

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Vitamin C: Anioxidant (fruit)

The health benefit of fruit juices have been ascribed, in part, to phenolic antioxidants.

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Vitamin C: Anioxidant (Disease)

Vitamin C in humans must be ingested for survival.

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Vitamin C: Anioxidant (comparision)

To express the antioxidant capacity of plant foods in a more familiar and easily understand manner ( equivalent to vitaminc C mg/100g), two stable radical species, ABTS and DPPH, commonly used for anitoxidant activity measurements, were employed independently to evaluate their efficacies using apple polyphenolic extracts and seven polyphenolic standards including synthetic Trolox.

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Vitamin C: Anioxidant (aqueous)

Free radical reactions occur in the human body and food systems.

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Vitamin C: AIDS

My previous experience with the utilization of ascorbic acid in the treatment of viral diseases led me to hypothesize that ascorbate would be of value in the treatment of AIDS (acquired immune deficiency syndrome).

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