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General Description

Sealantro is a proprietary blend of the extracts of three plants — Chlorella vulgaris, Cilantro (Coriandrum sativum), and Seaweed (Chondracanthus chamissoi).  This powerful combination of extracts detoxifies viral gastroenteritis and mobilizes and binds heavy metals, various radioactive substances, and other positively-charged toxins, especially in the gut.  This "gut binding" aids the elimination of those substances from the body.  Some specific metals eliminated by Sealantro include lead, arsenic, mercury, barium, cadmium, silver, nickel, aluminum, tin, titanium, radium, and indium.  Sealantro is an integral component of the Cowden Support Program, developed by W. Lee Cowden, MD to address chronic inflammatory conditions such as Lyme disease.

Some Reported Medicinal Properties











Research On NutraMedix Product

Medical Conditions [peer-reviewed journals]

Alzheimer’s Disease

Mani, V., Parle, M., Ramasamy, K., & Abdul Majeed, A. B. (2011). Reversal of memory deficits by Coriandrum sativum leaves in mice. Journal of the Science of Food and Agriculture, 91(1), 186-192. Full Article

Cardiovascular issues

Patel, D. K., Desai, S. N., Gandhi, H. P., Devkar, R. V., & Ramachandran, A. V. (2012). Cardio protective effect of Coriandrum sativum L. on isoproterenol induced myocardial necrosis in rats. Food and chemical toxicology, 50(9), 3120-3125. Full Article

Colon Cancer

Chithra, V., & Leelamma, S. (2000). Coriandrum sativum — effect on lipid metabolism in 1, 2-dimethyl hydrazine induced colon cancer. Journal of Ethnopharmacology, 71(3), 457-463. Full Article


Gray, A. M., & Flatt, P. R. (1999). Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander). British Journal of Nutrition, 81(3), 203-209. Full Article

Eidi, M., Eidi, A., Saeidi, A., Molanaei, S., Sadeghipour, A., Bahar, M., & Bahar, K. (2009). Effect of coriander seed (Coriandrum sativum L.) ethanol extract on insulin release from pancreatic beta cells in streptozotocin‐induced diabetic rats. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives,23(3), 404-406. Full Article


Wang, H. M., Pan, J. L., Chen, C. Y., Chiu, C. C.,Yang, M. H., Chang, H. W., & Chang, J. S. (2010). Identification of anti-lung cancer extract from Chlorella vulgaris CC by antioxidant property using supercritical carbon dioxide extraction. Process Biochemistry, 45(12), 1865-1872. Full Article


Hasegawa, T., Noda, K., Kumamoto, S., Ando, Y.,Yamada, A., & Yoshikai, Y. (2000). Chlorellavulgaris culture supernatant (CVS) reduces psychological stress-induced apoptosis in thymocytes of mice. International journal of immunopharmacology, 22(11), 877-885. Full Article

Medicinal Properties [peer-reviewed journals]


Mahendra, P., & Bisht, S. (2011). Anti-anxiety activity of Coriandrum sativum assessed using different experimental anxiety models. Indian Journal of Pharmacology, 43(5), 574. Full Article


Morimoto, T.,Nagatsu, A., Murakami, N., Sakakibara, J., Tokuda, H., Nishino, H., & Iwashima, A. (1995). Anti-tumour-promoting glyceroglycolipids from the green alga, Chlorella vulgaris. Phytochemistry, 40(5), 1433-1437. Full Article


Silva, F., Ferreira, S., Queiroz, J. A., & Domingues, F. C. (2011).Coriander (Coriandrum sativum L.) essential oil: its antibacterial activity and mode of action evaluated by flow cytometry. Journal of Medical Microbiology, 60(10), 1479-1486. Full Article

Saeed, S., & Tariq, P. (2007). Antibacterial activities of Emblica officinalis and Coriandrum sativum against Gram negative urinary pathogens. Pakistan Journal of Pharmaceutical Sciences, 20(1), 32-35. Abstract

Lo Cantore, P., Iacobellis, N. S., De Marco, A., Capasso, F., & Senatore, F. (2004). Antibacterial activity of Coriandrum sativum L. and Foeniculum vulgare Miller var. vulgare (Miller) essential oils. Journal of agricultural and food chemistry,52(26), 7862-7866. Full Article


de AlmeidaFreires, I., Murata, R. M., Furletti, V. F., Sartoratto, A., de Alencar, S. M., Figueira, G. M., ... & Rosalen, P. L. (2014). Coriandrum sativum L.(coriander) essential oil: antifungal activity and mode of action on Candida spp., and molecular targets affected in human whole-genome expression. PLoS One, 9(6), e99086. Full Article

Soares, B. V.,Morais, S. M., dos Santos Fontenelle, R. O., Queiroz, V. A., Vila-Nova, N. S.,Pereira, C., ... & Castelo-Branco, D. S. (2012). Antifungal activity, toxicity and chemical composition of the essential oil of Coriandrum sativum L. fruits. Molecules, 17(7), 8439-8448. Full Article

Silva, F.,Ferreira, S., Duarte, A., Mendonca, D. I., & Domingues, F. C. (2011). Antifungal activity of Coriandrum sativum essential oil, its mode of action against Candida species and potential synergism with amphotericin B. Phytomedicine, 19(1), 42-47. Full Article


Syed, S., Arasu, A., & Ponnuswamy, I. (2015). The uses of Chlorella vulgaris as antimicrobial agent and as a diet: the presence of bio-active compounds which caters the vitamins, minerals in general. Int J Biosci Biotechnol, 7(1), 185-190. Full Article

Rattanachaikunsopon, P., & Phumkhachorn, P. (2010). Potential of coriander (Coriandrum sativum) oil as a natural antimicrobial compound in controlling Campylobacter jejuni in raw meat. Bioscience, biotechnology, and biochemistry, 74(1), 31-35. Full Article

Begnami, A. F., Duarte, M. C. T., Furletti, V., & Rehder, V. L. G.(2010). Antimicrobial potential of Coriandrum sativum L. against different Candida species in vitro. Food chemistry, 118(1), 74-77. Full Article

Matasyoh, J. C., Maiyo, Z. C., Ngure, R. M., & Chepkorir, R.(2009). Chemical composition and antimicrobial activity of the essential oil of Coriandrum sativum. Food Chemistry, 113(2), 526-529. Full Article

Saeed, S., & Tariq, P. (2007). Antimicrobial activities of Emblica officinalis and Coriandrum sativum against gram positive bacteria and Candida albicans. Pak. J. Bot, 39(3), 913-917. Full Article


Emamghoreishi, M., Khasaki, M., & Aazam, M. F. (2005). Coriandrum sativum: evaluation of its anxiolytic effect in the elevated plus-maze. Journal of Ethnopharmacology, 96(3), 365-370. Full Article


Takyar, M. B. T., Khajavi, S. H., & Safari, R. (2019). Evaluation of antioxidant properties of Chlorella vulgaris and Spirulina platensis and their application in order to extend the shelf life of rainbow trout (Oncorhynchus mykiss) fillets during refrigerated storage. LWT, 100, 244-249. Full Article

Habashy, N. H., Serie, M. M. A., Attia, W. E., & Abdelgaleil, S. A.(2018). Chemical characterization, antioxidant and anti-inflammatory properties of Greek Thymus vulgaris extracts and their possible synergism with Egyptian Chlorella vulgaris. Journal of Functional Foods, 40, 317-328. Full Article

González-Marrugo, L. B., Granados-Llamas, E. A., Granados-Conde, C., Tejada-Tovar, C. N., & Ortega-Toro, R. (2018). Extraction and Evaluation of the Antioxidant Properties of Coriander (Coriandrum sativum) Seed Essential Oil. Full Article

Msaada, K., Jemia, M. B., Salem, N., Bachrouch, O., Sriti, J., Tammar, S., ... & Marzouk, B. (2017). Antioxidant activity of methanolic extracts from three coriander (Coriandrum sativum L.) fruit varieties. Arabian Journal of Chemistry, 10, S3176-S3183. Full Article

Baghdadi, H. H., El-Demerdash, F. M., Radwan, E. H., & Hussein, S.(2016). The protective effect of Coriandrum sativum L. oil against liver toxicity induced by ibuprofen in rats. J Biosci Appl Res, 2, 197-202. Full Article

Zeković, Z.,Vidović, S., Vladić, J., Radosavljević, R., Cvejin, A., Elgndi, M. A., & Pavlić, B. (2014). Optimization of subcritical water extraction of antioxidants from Coriandrum sativum seeds by response surface methodology. The Journal of Supercritical Fluids, 95, 560-566. Full Article

Tang, E. L., Rajarajeswaran, J., Fung, S. Y., & Kanthimathi, M. S. (2013). Antioxidant activity of Coriandrum sativum and protection against DNA damage and cancer cell migration. BMC complementary and alternative medicine, 13(1), 347. Full Article

Park, G., Kim,H. G., Kim, Y. O., Park, S. H., Kim, S. Y., & Oh, M. S. (2012). Coriandrum sativum L. protects human keratinocytes from oxidative stress by regulating oxidative defense systems. Skin pharmacology and physiology, 25(2), 93-99. Full Article

Divya, P.,Puthusseri, B., & Neelwarne, B. (2012). Carotenoid content, its stability during drying and the antioxidant activity of commercial coriander (Coriandrum sativum L.) varieties. Food Research International, 45(1), 342-350. Full Article

Darughe, F.,Barzegar, M., & Sahari, M. A. (2012). Antioxidant and antifungal activity of Coriander (Coriandrum sativum L.) essential oil in cake. International Food Research Journal, 19(3), 1253-1260. Full Article

Deepa, B.,& Anuradha, C. V. (2011). Antioxidant potential of Coriandrum sativum L. seed extract. Indian Journal of Experimental Biology. Full Article

Sreelatha, S., Padma, P. R., & Umadevi, M. (2009). Protective effects of Coriandrum sativum extracts on carbon tetrachloride-induced hepatotoxicity in rats. Food and Chemical Toxicology, 47(4), 702-708. Full Article

Vijayavel, K., Anbuselvam, C., & Balasubramanian, M. P. (2007). Antioxidant effect of the marine algae Chlorella vulgaris against naphthalene-induced oxidative stress in the albino rats. Molecular and cellular biochemistry, 303(1-2), 39-44. Full Article

Wong, P. Y., & Kitts, D. D. (2006). Studies on the dual antioxidant and antibacterial properties of parsley (Petroselinum crispum) and cilantro (Coriandrum sativum) extracts. Food chemistry, 97(3),505-515. Full Article

Guerra, N. B., de Almeida Melo, E., & Mancini Filho, J. (2005). Antioxidant compounds from coriander (Coriandrum sativum L.) etheric extract. Journal of Food Composition and Analysis, 18(2-3), 193-199. Full Article

de Almeida Melo, E., Mancini Filho, J., & Guerra, N. B. (2005). Characterization of antioxidant compounds in aqueous coriander extract (Coriandrum sativum L.). LWT-Food Science and Technology, 38(1), 15-19. Full Article

Hashim, M. S., Lincy, S., Remya, V., Teena, M., & Anila, L. (2005). Effect of polyphenolic compounds from Coriandrum sativum on H2O2-induced oxidative stress in human lymphocytes. Food Chemistry, 92(4),653-660. Full Article

de Almeida Melo, E., Bion, F. M., Filho, J. M., & Guerra, N. B. (2003). In vivo antioxidant effect of aqueous and etheric coriander (Coriandrum sativum L.) extracts. European Journal ofLipid Science and Technology, 105(9), 483-487. Full Article

Ramadan, M. F., Kroh, L. W., & Mörsel, J. T. (2003). Radical scavenging activity of black cumin (Nigella sativa L.), coriander (Coriandrum sativum L.), and niger (Guizotia abyssinica Cass.) crude seed oils and oilfractions. Journal of agricultural and food chemistry, 51(24), 6961-6969. Full Article

Chithra, V.,& Leelamma, S. (1999). Coriandrum sativum changes the levels of lipid peroxides and activity of antioxidant enzymes in experimental animals. Indian Journal of Biochemistry & Biophysics. Full Article


Eguale, T., Tilahun, G., Debella, A., Feleke, A., & Makonnen, E.(2007). In vitro and in vivo anthelmintic activity of crude extracts of Coriandrum sativum against Haemonchus contortus. Journal of Ethnopharmacology, 110(3), 428-433. Full Article


Sonika, G., Manubala, R., & Deepak, J. (2010). Comparative studies on anti-inflammatory activity of Coriandrum Sativum, Datura stramonium and Azadirachta Indica. Asian J Exp Biol Sci, 1(1), 151-154. Full Article

Chelating effects

Queiroz, M. L., Rodrigues, A. P., Bincoletto, C., Figueirêdo, C. A.,& Malacrida, S. (2003). Protective effects of Chlorella vulgaris in lead-exposed mice infected with Listeria monocytogenes. International immunopharmacology, 3(6), 889-900. Full Article


Dhanapakiam, P., Joseph, J. M., Ramaswamy, V. K., Moorthi, M., & Kumar, A. S. (2007). The cholesterol-lowering property of coriander seeds (Coriandrum sativum): mechanism of actionJournal of Environmental Biology, 29(1), 53. Full Article


Pandey, A., Bigoniya, P., Raj, V., & Patel, K. K. (2011). Pharmacological screening of Coriandrum sativum Linn. for hepatoprotective activity. Journal of Pharmacy and Bioallied sciences, 3(3), 435. Full Article


Morris, H. J., Carrillo, O., Almarales, A., Bermúdez, R. C., Lebeque, Y., Fontaine, R., ... & Beltrán, Y. (2007). Immunostimulant activity of an enzymatic protein hydrolysate from green microalga Chlorella vulgaris on undernourished mice. Enzyme and Microbial Technology, 40(3), 456-460. Full Article

Various Properties

Sathishkumar, P., Preethi, J., Vijayan, R., Yusoff, A. R. M., Ameen, F., Suresh, S., ... & Palvannan, T. (2016). Anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised silver nanoparticles using Coriandrum sativum leaf extract. Journal of Photochemistry and Photobiology B: Biology, 163, 69-76. Full Article

Rajeshwari, U., & Andallu, B. (2011). Medicinal benefits of coriander (Coriandrum sativum L). Spatula DD, 1(1), 51-58. Full Article

Mizoguchi, T., Takehara, I., Masuzawa, T., Saito, T., & Naoki, Y.(2008). Nutrigenomic studies of effects of Chlorella on subjects with high-risk factors for lifestyle-related disease. Journal of medicinal food, 11(3),395-404. Full Article

Singh, G., Maurya, S., De Lampasona, M. P., & Catalan, C. A.(2006). Studies on essential oils, Part41. Chemical composition, antifungal, antioxidant and sprout suppressant activities of coriander (Coriandrum sativum) essential oil and its oleoresin. Flavour and fragrance journal, 21(3), 472-479. Full Article

Medicinal Properties
[other journals]

Medical Conditions [other journals]


Conference Presentations

Dublin, Ireland – June, 2012 Armin Schwarzbach, MD PhD

Patient Reports

"For over four years, I was exhausted and I couldn't figure out why.  The doctor finally told me I had candida overgrowth.  I took some products to help, but I still was tired.  My sister gave me a bottle of Sealantro, and my energy came back and I feel like my old self again." -I.N.

Dosage Information

40 drops every other day 30 minutes before a meal; use in 4 oz. of water.


Safety Information

Product Label

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Coriandrum sativum: Variouos properties (acne)

Silver nanoparticles (AgNPs) are finding rich applications in various area including nanodevices, nanoelectronics, nanosensors, information storage, biomedical treatments and water purification.

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Coriandrum sativum: Variouos properties (41)

The growing interest in the substitution of ‘traditional food preservatives’, both antimicrobials and antioxidants, by natural ones has fostered research on vegetable sources and the screening of plant materials. It has been known since ancient times that spices and their essential oils have varying degrees of antimicrobial activity.

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Coriandrum sativum: Hepatoprotective

The liver is an organ of paramount importance and plays an essential role in the metabolism of foreign compounds entering the body. Human beings are being exposed to these compounds through environment exposure, consumption of contaminated food or during exposure to chemical substances in the occupational environment.

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Coriandrum sativum: Diabetes (insulin)

Coriander (Coriandrum sativum L.) is grown as a spice crop all over the world. The seeds have been used to treat indigestion, diabetes, rheumatism and pain in the joints. In the present study, an ethanol extract of the seeds was investigated for effects on insulin release from the pancreatic beta cells in streptozotocin-induced diabetic rats.

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Coriandrum sativum: Colon cancer

The biochemical effect of coriander seeds on lipid parameters in 1,2-dimethyl hydrazine (DMH) induced colon cancer in rats were studied. The study shows that the concentrations of cholesterol and cholesterol to phospholipid ratio decreased while the level of phospholipid increased significantly in the DMH control group compared to the spice administered group.

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Coriandrum sativum: Cardiovascular issues

The preventive effect of Coriandrum sativum L. (CS) on cardiac damage was evaluated by Isoproterenol (IP) induced cardiotoxicity model in male Wistar rats. Rats were pretreated with methanolic extract of CS seeds at a dose of 100, 200 or 300 mg/kg orally for 30 days and they were subsequently administered (s.c.) with IP (85 mg/kg body weight) for the last two days.

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Coriandrum sativum: Antioxidant (surface)

Coriander (Coriandrum sativum L.) is aromatic plant which is widely distributed and cultivated in Mediterranean countries. The coriander seeds contain an essential oil (up to 1%), where monoterpenoid linalool is the main compound (>50%), and limonene, camphor and geraniol are present in significant quantity.

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Coriandrum sativum: Antioxidant (H2O2)

There is great interest in plant polyphenolic com-pounds because of their potential roles as cancer chem-opreventive agents and chronic disease protectors. Their beneficial effect is considered to be mainly due to their antioxidant and chelating activities.

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Coriandrum sativum: Antioxidant (etheric)

Research has shown that aqueous and etheric coriander extracts, composed of phenolics and carotenoids, exhibit a considerable antioxidant action. Considering the importance of natural antioxidants in the reduction of free radicals and oxidised com-pounds, coriander extracts obtained through sequential extraction, were administered by gavage to Wistar rats during 30 and 60 d consecutively.

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Coriandrum sativum: Antioxidant (DNA)

Plants have played a significant role in providing the hu-man race with remedies. At present, phytotherapy is a recognised complementary and alternative medicinal (CAM) therapeutic modality. It is one of the promising fields in health care as supportive medicine in the treatment of diseases like cancer.

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Coriandrum sativum: Antioxidant (defense)

Background: Oxidative radicals are major environmental causes of human skin damage. Oxidative defense factors, in-cluding nuclear factor erythroid-derived 2-related factor 2 (Nrf2), are centrally involved in repairing skin cells or protecting them from oxidative damage.

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Coriandrum sativum: Antioxidant (compounds)

Five fractions (b-carotene, b-cryptoxanthin epoxide, lutein-5,6-epoxide, violaxanthin and neoxanthin) were isolated from a coriander ether extract using column chromatography and identified according to their chromatographic and spectral characteristics.

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Coriandrum sativum: Antioxidant (commercial)

Coriander, also popular as Cilantro or Chinese Parsley, is an aromatic annual herb (of Apiaceae or Umbelliferae) cultivated for its seeds and foliage which are used all over the world as culinary spice, flavoring agent and for its various medicinal/aromatic applications.

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Coriandrum sativum: Antioxidant (Carbon)

Liver is the first organ to metabolise all foreign compounds and hence it is susceptible to almost as many different diseases. Some are rare but there are a few, including hepatitis, cirrhosis, alcohol-related disorders and liver cancer.

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Coriandrum sativum: Antioxidant (aqueous)

An aqueous coriander extract obtained through a sequential extraction process, was analysed using chromatography and mass spectrometry in order to identify the phenolic compounds responsible for its antioxidant activity.

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Coriandrum sativum: Antimicrobial (raw)

Twelve essential oils were tested in vitro for anti-microbial activities against several strains of Campylobacter jejuni, a pathogen causing food-borne diseases worldwide. Using disk diffusion and minimal inhibitory concentration determination assays, we noted that coriander oil exhibited the strongest antimicrobial activity against all tested strains.

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Coriandrum sativum: Anti-inflammatory

For the screening of anti–inflammatory activity, the plants which were used are Coriandrum sativum Linn is commonly known as Dhania or Dhana (Umbelliferae). It yields 0.3 to1% of volatile oil, 90% of D- linalool, coriandryl acetate, L-borneol, geraniol and pinene.

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Coriandrum sativum: Antifungal (Genome)

This is a bio-guided study investigating the antifungal susceptibility of Candida spp. to the action of C. sativum EO and its active fraction.

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Coriandrum sativum: Antifungal (composition)

Dermatophytosis is one of the most frequent skin diseases of pets and livestock. Contagion among animal communities, high treatment cost, difficulties of control measures and public health consequences of animal ringworm are all factors urging the study of these fungi.

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Coriandrum sativum: Alzheimers

Alzheimer’s disease (AD) is a genetically heterogeneous, crippling neurodegenerative disorder, which is slow in onset but relentless in progress.

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Chlorella vulgaris: Stress

Chlorella, a unicellular green algae, can divide into four cells every 16–20 h, utilizing sunlight for photosynthesis. Chlorella cells contain 55–67%protein, 1–4% chlorophylls, 9–18% dietary fiber and large amounts of minerals and vitamins.

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Chlorella vulgaris: Lung cancer

The free radicals and reactive oxygen species (ROS) generated by microsomal metabolism may augment an oxidative stress by the formation of hydrogen peroxide or superoxide anions in human beings.

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Chlorella vulgaris: Immunomodulating

Enzymatic protein hydrolysates have been reported as suitable sources of protein for human nutrition because of their gastrointestinal absorption, which seems to be more effective than both intact protein and free amino acids.

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Chlorella vulgaris: Chelating effects

Chlorella vulgaris, a unicellular green algae, has been studied in a variety of practical approaches. In the last years, several reports from our laboratory and others demonstrated the protective effects of this algae against bacterial and virus infections, tumours and peptic ulcers.

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Chlorella vulgaris: Antioxidant (trout)

Fish is a valuable source of protein and contains high amounts of ω-3 polyunsaturated fatty acids (PUFAs) which play an important role in a healthy diet (Avadi & Freon, 2015). Generally, due to the high amounts of free amino acids, volatile basic nitrogen and PUFAs in fish, they are more perishable compared to red meat and poultry meat (Hoel, Jakobsen, & Vadstein, 2017).

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Chlorella vulgaris: Antioxidant (Greek)

Oxidative stress is the imbalance between the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) and their clearance by the antioxidants.

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Chlorella vulgaris: Antioxidant (albino)

Alcoholic extract of the marine algae Chlorella vulgaris was examined for its free radical scavenging effect with reference to naphthalene-induced lipid peroxidation in serum, liver, and kidney of rats.

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Chlorella vulgaris: antimicrobial (diet)

The extracted and dried green micro algae by using solvents Acetone, Ethanol and Chloroform assy is tested to know its efficiency against four bacterial strains under the cultured condions by adopting the standard agar disc diffusion technique.

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Sealantro: Coriandrum sativum - Antioxidant (three)

In this work, we evaluated for the first time the total polyphenols, flavonoids and condensed tannin contents and the antioxidant potential of the methanolic extracts of coriander fruit by DPPH, reducing power and b-carotene/linoleic acid assays.

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Sealantro: Coriandrum sativum - antioxidant (ibuprofen)

Ibuprofen (IBU) is a Non-steroidal anti-inflammatory drug used in the treatment of pain, fever and in inflammation.Coriandrum sativum is cultivated for its aromatic and medicinal uses. The present study aims to evaluate the protective effect of Coriandrum sativum volatile oil on hepatotoxicity of IBU in rats. Five groups of albino rats were used.

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Sealantro: Coriandrum sativum - Antioxidant (extraction)

In the present work, the antioxidant activity of coriander (Coriandrum sativum) seed oil was evaluated for its later use as a natural additive. The extraction of the oil was done by the Soxhlet method, then the major components were identified by Gas Chromatography coupled to Mass Spectrometry, and DPPH determined their antioxidant activity.

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Sealantro: Coriandrum sativum - diabetes (traditional)

Coriandrum sativum (coriander) has been documented as a traditional treatment of diabetes. In the present study, coriander incorporated into the diet (62⋅5 g/kg) and drinking water (2⋅5 g/l, prepared by 15 min decoction) reduced hyperglycaemia of streptozotocin-diabetic mice.

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Sealantro: Antioxidant potential of Coriandrum sativum L. seed extract

The seeds of C. sativum are used as a traditional drug for the treatment of diabetes. The antioxidant and free-radical-scavenging property of seeds in vitro was studied and also investigated whether the administration of seeds curtails oxidative stress in the kidney of streptozotocin-induced diabetic rats. Incorporation of seed powder in the diet led to marked lowering of blood glucose and a rise in the levels of insulin in diabetic rats.

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Sealantro: Antimicrobial activities of Emlica Officinalis

Present investigation focused on antimicrobial potential of aqueous infusions and aqueous decoctions of Emblica officinalis (amla) and Coriandrum sativum (coriander) against 186 bacterial isolates belonging to 10 different genera of G +ve bacterial population and 2 isolates of Candida albicans isolated from urine specimens.

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Sealantro: Broad Spectrum (benifits)

Medicinal plants have therapeutic potential due to the presence of natural antioxidants functioning as reducing agents, free radical scavengers and quenchers of singlet oxygen. Majority of their antioxidant activity is due to bioactive compounds viz. flavones, isoflavones, flavonoids, anthocyanins, coumarins, lignans, catechins and isocatechins. Currently there has been an increasing interest to identify the antioxidants that are pharmacologically potent with low or no side effects for use in preventive medicine.

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Sealantro: Antioxidant

Lipid peroxidation is a complex process which is initiated by abstraction of hydrogen atoms from unsaturated fatty acids of phospholipid and lipoprotein complexes yielding conjugated dienes. The conjugated dienes then react with molecular oxygen to produce peroxy radicals which propagate the chain reaction by abstracting hydrogen from other unsaturated Iipids.

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Sealantro: Antioxidant (Radical)

The positive relationship observed between the RSA of crude oils and their color intensity suggests the Maillard reaction products may have contributed to the RSA of seed oils and their polar fractions. The results demonstrate the importance of minor components in crude seed oils on their oxidative stability, which will reflect on their food value and shelf life. As part of the effort to assess the potential of these seed oils, the information is also of importance in processing and utilizing the crude oils and their byproducts.

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Sealantro: Antioxidant (Dual)

Antioxidant and antibacterial activities of freeze-dried and irradiated parsley (Petroselinum crispum) and cilantro (Coriandrum sativum) leaves and stems were determined on methanol and water extracts. The total phenolic content was quantified with the Folin–Ciocalteau reagent. Several mechanisms of potential antioxidant activity of all extracts, including determining relative free radical-scavenging and ferrous ion-chelating activities, as well as reducing power, were examined.

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Sealantro: Antioxidant (cake)

In recent years, essential oils have been qualified as natural antioxidants and proposed as potential substitutes of synthetic antioxidants in food preservation. The safety of the synthetic antioxidants has been doubted. In this study essential oil of coriander were analyzed by GC/MS and its chemical compositions were identifed. Camphor (44.99%), cyclohexanol acetate (cis-2-tert.butyl-) (14.45%), limonene (7.17%), α-pinene (6.37%), were the main components of coriander essential oil (CEO).

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Sealantro: Antifungal (synergism)

The increasing incidence of drug-resistant pathogens and toxicity of existing antifungal compounds has drawn attention towards the antimicrobial activity of natural products. The aim of the present study was to evaluate the antifungal activity of coriander essential oil according to classical bacteriological techniques, as well as with flow cytometry.

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Sealantro: Antibacterial (cytomety)

The aim of this work was to study the antibacterial effect of coriander (Coriandrum sativum) essential oil against Gram-positive and Gram-negative bacteria. Antibacterial susceptibility was evaluated using classical microbiological techniques concomitantly with the use of flow cytometry for the evaluation of cellular physiology.

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Sealantro: Anti-anxiety

Interest in alternative medicine and plant-derived medications that affect the “mind” is growing. The aim of present study was to explore the anti-anxiety activity of hydroalcoholic extract of Coriandrum sativum (Linn.) using different animal models (elevated plus maze, open field test, light and dark test and social interaction test) of anxiety in mice.

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Sealantro: Anthelmintic

In vitro anthelmintic activities of crude aqueous and hydro-alcoholic extracts of the seeds of Coriandrum sativum (Apiaceae) were investigated on the egg and adult nematode parasite Haemonchus contortus. The aqueous extract of Coriandrum sativum was also investigated for in vivo anthelmintic activity in sheep infected with Haemonchus contortus.

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Sealantro: Broad Spectrum

In order to clarify the physiological effects of Chlorella intake on subjects with high-risk factors for lifestyle-related diseases, we conducted Chlorella ingestion tests on 17 subjects with high-risk factors for lifestyle-related diseases and 17 healthy subjects over a 16-week period, including a 4-week post-observation period.

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Sealantro: antitumor

As a part of our continuing search for galactolipids as anti-tumour promoters, we found that glyceroglycolipids from the freshwater green alga, C. vul#aris, inhibited tumor promotion more effectively than those from P. tenue. In this paper, we present the isolation and structural elucidation of the anti-tumour-promoting glyceroglycolipids from C. vulgaris.

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Sealantro: Cholesterol Lowering

Coriandrum sativum (Coriander) has been documented as a traditional treatment for cholesterol and diabetes patients. In the present study, coriander seeds incorporated into diet and the effect of the administration of coriander seeds on the metabolism of lipids was studied in rats, fed with high fat diet and added cholesterol.

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Sealantro: Anxiolytic Effect

The clinical applications of benzodiazepines as anxiolytics are limited by their unwanted side effects. Therefore, the development of new pharmacological agents is well justified. Among medicinal plants, Coriandrum sativum L. has been recommended for relief of anxiety and insomnia in Iranian folk medicine. Nevertheless, no pharmacological studies have thus far evaluated its effects on central nervous system.

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Sealantro: Antimicrobial Potential

The aim of this study was to evaluate the chemical and antifungal activity of the essential oil from Coriandrum sativum L. (Apiaceae) against different Candida species. The essential oil (EO) was obtained by hydrodistillation and submitted to dry-column chromatography, resulting in six fractions, which were then submitted to TLC and GC–MS analysis.

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Sealantro: Antimicrobial Activity

The essential oil from leaves of Coriandrum sativum L. (Apiaceae), obtained by hydro-distillation was analysed by gas chromatography–mass spectrometry (GC–MS) and also evaluated for in vitro antimicrobial activity. Out of 27 peaks, 24 components, which constitute 92.7%, were identified in the oil.

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Sealantro: Antibacterial Activity

Essential oils were extracted from the fruits of Coriandrum sativum L. and Foeniculum vulgare Miller var. vulgare (Miller) and assayed in vitro for antibacterial activity to Escherichia coli and Bacillus megaterium, bacteria routinely used for comparison in the antimicrobial assays, and 27 phytopathogenic bacterial species and two mycopathogenic ones responsible for cultivated mushroom diseases.

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