Crude extracts of root, leaf and fruit of Morinda citrifolia were fractionated on a Sephadex LH-20 column with ethanol as eluate. Based on UV absorption intensity of phenolic compound (725 mm) the Sephadex LH-20 column was able to separate fruit, leaf and root extracts into six, ﬁve and ﬁve fractions, respectively. The results showed that all the fractions tested exhibited considerably high antioxidative activity in the ferric thiocyanate assay and thiobarbituric acid test and the activities of some of the fractions were as good as those of either tocopherol or BHT. The fractions from diﬀerent parts of the plants were found to contain diﬀerent amounts of total phenolic compounds, which, interestingly, do not correspond to the antioxidative activity measured. This is probably due to the presence of diﬀerent phenolics in the samples, with diﬀerent antioxidative activities which involves various mechanisms inhib-iting the oxidation process. The study suggested that root, leaf and fruit of M. citrifolia might contribute signiﬁcantly to exogenous antioxidant which is crucial in combating oxidative stress.