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TAKUNA

MICROBIAL DEFENSE

FOR FIGHTING:

  • COLDS
  • FLU
  • VIRAL HEPATITIS
  • SHINGLES
  • CYTOMEGALOVIRUS
  • EPSTEIN-BARR VIRUS
  • ACUTE AND CHRONIC VIRAL ENCEPHALITIS AND MENINGITIS
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General Description

Takuna is an extract produced from the bark of Cecropia strigosa, a tree that is found throughout South America. It has recently been found to have very powerful antiviral properties as well as some other general antimicrobial properties. Practitioners using the product have found that Takuna given every hour usually resolves influenzas in just a few hours. In some cases, the symptoms are resolved in as little as one hour. Practitioners also report that Takuna is effective against some bacterial infections and some fungal infections.

Some Reported Medicinal Properties

ANTI-AMENORRHEAL

ANTI-ASTHMATIC

ANTIBACTERIAL

ANTI-DIABETIC

ANTI-FEVER

ANTI-FREE RADICALS

ANTIFUNGAL

ANTI-HYPERPLASIA

ANTI-INFLAMMATORY

ANTI-MUCOSAL

ANTIOXIDANT

ANTI-PAIN

ANTI-PARKINSONISM

ANTI-SPASMODIC

ANTIVIRAL

DECONGESTANT

HYPOTENSIVE

PURGATIVE

Research On NutraMedix Product

In vitro – Lyme Disease

Priyanka A.S. Theophilus M.S., Eva Sapi Ph.D. (2013). In Vitro Effect of Peruvian Antimicrobial Agents on Borrelia burgdorferi Full Article

in vivo – Anti-inflammatory

At the University of Guayaquil, Ecuador, Takuna produced an anti-inflammatory effect 73% as strong as Feldeneas an anti-inflammatory. Full Article

in vivo acute oral toxicity tests

An Acute Oral toxicity study was conducted by the Department of Chemical Sciences at the University of Guayaquil, Ecuador.  The general conclusion was that Takuna did not produce toxic effects when used in accordance to the guidelines described in OECD TG 423, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article 

Medical Conditions [peer-reviewed journals]

Adjunctive to Chemotherapy

Miranzadeh,S., Adib-Hajbaghery, M., Soleymanpoor, L., & Ehsani, M. (2015). Effect of adding the herb Achilleamillefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial. European Journal of Oncology Nursing, 19(3), 207-213. Full Article

Anxiety

Fernández-Demeneghi, R., Rodríguez-Landa, J. F., Guzmán-Gerónimo,R. I., Acosta-Mesa, H. G., Meza-Alvarado, E., Vargas-Moreno, I., &Herrera-Meza, S. (2019). Effect of blackberry juice (Rubus fruticosus L.) on anxiety-like behaviour in Wistar ratsInternational journal of food sciences and nutrition, 1-12. Full Article

Cancer

Amini Navaie, B., Kavoosian, S., Fattahi, S., Hajian-Tilaki, K., Asouri, M.,Bishekolaie, R., & Akhavan-Niaki, H. (2015). Antioxidant and cytotoxic effect of aqueous and hydroalcoholic extracts of the Achillea millefolium L. on MCF-7 breast cancer cell line. International Biological and Biomedical Journal, 1(3), 119-125. Full Article

Antioxidant

Villalva, M., Jaime, L., Villanueva-Bermejo,D., Lara, B., Fornari, T., Reglero, G., & Santoyo, S. (2019). Supercritical anti-solvent fractionation for improving antioxidant and anti-inflammatory activities of an Achillea millefolium L. extractFoodResearch International115, 128-134. Full Article

Monforte, M. T., Smeriglio, A.,Germanò, M. P., Pergolizzi, S., Circosta, C., & Galati, E. M. (2018). Evaluation of antioxidant, antiinflammatory, and gastroprotective properties of Rubus fruticosus L. fruit juicePhytotherapy research32(7), 1404-1414. Full Article

Antitumor

Pereira, J. M., Peixoto, V., Teixeira,A., Sousa, D., Barros, L., Ferreira, I. C., & Vasconcelos, M. H.(2018). Achillea millefolium L. hydroethanolic extract inhibits growth of human tumor cell lines by interfering with cell cycle and inducing apoptosis. Food and Chemical Toxicology. Full Article

Antimutagenic

Hussein, A. A., Al-Ezzy, R. M., & Abdallah, M. T. (2019). Biochemical, Enzymatic, and Immunological Study on Antimutagenic Achillea millefolium Methanolic Extract in vivo. Journal of Pharmacy and Pharmacology,7, 69-74. Full Article

Multiple Sclerosis

Ayoobi, F., Moghadam-Ahmadi, A.,Amiri, H., Vakilian, A., Heidari, M., Farahmand, H., ... & Shamsizadeh, A.(2019). Achillea millefolium is beneficial as an add-on therapy in patients with multiple sclerosis: A randomized placebo-controlled clinical trial. Phytomedicine, 52, 89-97. Full Article

Medicinal Properties [peer-reviewed journals]

ANTIOXIDANT

Pavithra, S., & Banu, N. (2017). Free Radical Scavenging Activity and Total Antioxidant Capacity of Tin Chlorophyllin from Morinda citrifolia L. Research Journal of Pharmacy and Technology, 10(2), 453-455. Full Article

Krishnaiah, D., Bono, A., Sarbatly, R., & Anisuzzaman, S. M. (2015). Antioxidant activity and total phenolic content of an isolated Morinda citrifolia L. methanolic extract from Poly-ethersulphone (PES) membrane separator. Journal of King Saud University-Engineering Sciences, 27(1), 63-67. Full Article

de Almeida Brito, F., de Oliveira Barreto, E., Serafini, M. R., dos Santos, J. P. A., dos Santos Lima, B., Walker, C. I. B., ... & de Souza Araujo, A. A. (2015). Anti-inflammatory property and redox profile of the leaves extract from Morinda citrifolia L. Journal of Medicinal Plants Research, 9(24), 693-701. Full Article

Piaru, S. P., Mahmud, R., Abdul Majid, A. M., & Mahmoud Nassar, Z. D. (2012). Antioxidant and antiangiogenic activities of the essential oils of Myristica fragrans and Morinda citrifolia. Asian Pac J Trop Med, 5(4), 294-298. Full Article

Serafini, M. R., Santos, R. C., Guimaraes, A. G., dos Santos, J. P. A., da Conceicao Santos, A. D., Alves, I. A., ... & de Souza Araújo, A. A. (2011). Morinda citrifolia Linn leaf extract possesses antioxidant activities and reduces nociceptive behavior and leukocyte migration. Journal of Medicinal Food, 14(10), 1159-1166. Full Article

Masuda, M., Murata, K., Fukuhama, A., Naruto, S., Fujita, T., Uwaya, A., ... & Matsuda, H. (2009). Inhibitory effects of constituents of Morinda citrifolia seeds on elastase and tyrosinase. Journal of Natural Medicines, 63(3), 267-273. Full Article

Liu, C. H., Xue, Y. R., Ye, Y. H., Yuan, F. F., Liu, J. Y., & Shuang, J. L. (2007). Extraction and characterization of antioxidant compositions from fermented fruit juice of Morinda citrifolia (Noni). Agricultural Sciences in China, 6(12), 1494-1501. Full Article

Ramamoorthy, P. K., & Bono, A. (2007). Antioxidant activity, total phenolic and flavonoid content of Morinda citrifolia fruit extracts from various extraction processes. Journal of Engineering Science and Technology, 2(1), 70-80. Full Article

Yang, J. I. A. N., Gadi, R. A. M. A., & Thomson, T. A. L. E. N. E. (2011). Antioxidant capacity, total phenols, and ascorbic acid content of noni (Morinda citrifolia) fruits and leaves at various stages of maturity. Micronesica, 41(2), 167-176. Full Article

Yang, J., Paulino, R., Janke-Stedronsky, S., & Abawi, F. (2007). Free-radical-scavenging activity and total phenols of noni (Morinda citrifolia L.) juice and powder in processing and storage. Food Chemistry, 102(1), 302-308. Full Article

Zin, Z. M., Abdul-Hamid, A., & Osman, A. (2002). Antioxidative activities of chromatographic fractions obtained from root, fruit and leaf of Mengkudu (Morinda citrifolia L.) Food Chemistry, 78(2), 227-231. Full Article

ANTIDEPRESSENT

Deng, S., & West, B. J. (2011). Antidepressant effects of noni fruit and its active principals. Asian J Med Sci, 3(2), 79-83. Full Article

ANTIFUNGAL

Jainkittivong, A., Butsarakamruha, T., & Langlais, R. P. (2009). Antifungal activity of Morinda citrifolia fruit extract against Candida albicans. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 108(3), 394-398. Full Article

ANTIBACTERIAL

Silva, A. R. N., Ranaweera, C. B., Karunathilaka, R. N., Pathirana, R., & Ratnasooriya, W. D. (2016). Antibacterial activity of water extracts of different parts of Morinda citrifolia grown in Sri Lanka. Int J Sci Res Publ, 6, 124-7. Full Article

Schäfer, M., Sharp, P., Brooks, V. J., Xu, J., Cai, J., Keuler, N. S., ... & Darien, B. J. (2008). Enhanced bactericidal activity against Escherichia coli in calves fed Morinda citrifolia (Noni) puree. Journal of veterinary internal medicine, 22(2), 499-502. Full Article

Jayaraman, S. K., Manoharan, M. S., & Illanchezian, S. (2008). Antibacterial, antifungal and tumor cell suppression potential of Morinda citrifolia fruit extracts. International Journal of Integrative Biology, 3(1), 44-49. Full Article

De La Cruz-Sánchez, N. G., Gómez-Rivera, A., Alvarez-Fitz, P.,Ventura-Zapata, E., Pérez-García, M. D., Avilés-Flores, M., ... &González-Cortazar, M. (2019). Antibacterial activity of Morinda citrifolia Linneo seeds against Methicillin-ResistantStaphylococcus sppMicrobial pathogenesis128,347-353. Full Article

ANTI-TUMOR

Furusawa, E., Hirazumi, A., Story, S., & Jensen, J. (2003). Antitumour potential of a polysaccharide‐rich substance from the fruit juice of Morinda citrifolia (Noni) on sarcoma 180 ascites tumour in mice. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 17(10), 1158-1164. Full Article

ANTIULCER

Muralidharan, P., & Srikanth, J. (2009). Antiulcer activity of Morinda citrifolia Linn fruit extract. J Sci Res, 1(2), 345-352. Full Article

ANTIMICROBIAL

Usha, R., Sashidharan, S., & Palaniswamy, M. (2010). Antimicrobial Activity of a Rarely Known Species, Morinda citrifolia L. Ethnobotanical Leaflets, 2010(3), 7. Full Article

ANTI-INFLAMMATORY

Sousa, S. G., Oliveira, L. A., de Aguiar Magalhães, D., de Brito, T. V., Batista, J. A., Pereira, C. M. C., ... & da Silva, D. A. (2018). Chemical structure and anti-inflammatory effect of Polysaccharide extracted from Morinda citrifolia Linn (Noni). Carbohydrate Polymers. Full Article

Dussossoy, E., Bichon, F., Bony, E., Portet, K., Brat, P., Vaillant, F., ... & Poucheret, P. (2016). Pulmonary anti-inflammatory effects and spasmolytic properties of Costa Rican noni juice (Morinda citrifolia L.). Journal of Ethnopharmacology, 192, 264-272. Full Article

Huang, H. L., Liu, C. T., Chou, M. C., Ko, C. H., & Wang, C. K. (2015). Noni (Morinda citrifolia L.) fruit extracts improve colon microflora and exert anti-inflammatory activities in Caco-2 cells. Journal of medicinal food, 18(6), 663-676. Full Article

Nitteranon, V., Zhang, G., Darien, B. J., & Parkin, K. (2011). Isolation and synergism of in vitro anti-inflammatory and quinone reductase (QR) inducing agents from the fruits of Morinda citrifolia (noni). Food research international, 44(7), 2271-2277. Full Article

Dussossoy, E., Brat, P., Bony, E., Boudard, F., Poucheret, P., Mertz, C., ... & Michel, A. (2011). Characterization, anti-oxidative and anti-inflammatory effects of Costa Rican noni juice (Morinda citrifolia L.). Journal of ethnopharmacology, 133(1), 108-115. Full Article

Basar, S., Uhlenhut, K., Högger, P., Schöne, F., & Westendorf, J. (2010). Analgesic and antiinflammatory activity of Morinda citrifolia L.(Noni) fruit. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 24(1), 38-42. Full Article

Akihisa, T., Matsumoto, K., Tokuda, H., Yasukawa, K., Seino, K. I., Nakamoto, K., ... & Kimura, Y. (2007). Anti-inflammatory and potential cancer chemopreventive constituents of the fruits of Morinda citrifolia (Noni). Journal of Natural Products, 70(5), 754-757. Full Article

Mckoy, M. G., Thomas, E. A., & Simon, O. R. (2002). Preliminary investigation of the anti-inflammatory properties of an aqueous extract from Morinda citrifolia (Noni). In Proceedings of the Western Pharmacology Society (Vol. 45, pp. 76-78). Seattle, Wash.: The Society. Full Article

ATHLETIC ENDURANCE

Anekpankul, T., Goto, M., Sasaki, M., Pavasant, P., & Shotipruk, A. (2007). Extraction of anti-cancer damnacanthal from roots of Morinda citrifolia by subcritical water. Separation and Purification Technology, 55(3), 343-349. Full Article

HEPATOTOXICITY

Wang, M. Y., Anderson, G., Nowicki, D., & Jensen, J. (2008). Hepatic protection by noni fruit juice against CCl 4-induced chronic liver damage in female SD rats. Plant foods for human nutrition, 63(3), 141-145. Full Article

Stadlbauer, V., Fickert, P., Lackner, C., Schmerlaib, J., Krisper, P., Trauner, M., & Stauber, R. E. (2005). Hepatotoxicity of NONI juice: report of two cases. World journal of gastroenterology: WJG, 11(30), 4758. Full Article

IMMUNOMODULATING

Palu, A. K., Kim, A. H., West, B. J., Deng, S., Jensen, J., & White, L. (2008). The effects of Morinda citrifolia L.(noni) on the immune system: its molecular mechanisms of action. Journal of Ethnopharmacology, 115(3), 502-506. Full Article

Nayak, S., & Mengi, S. (2010). Immunostimulant activity of noni (Morinda citrifolia) on T and B lymphocytes. Pharmaceutical biology, 48(7), 724-731. Full Article

MEMORY IMPROVEMENT

Pachauri, S. D., Tota, S., Khandelwal, K., Verma, P. R. P., Nath, C., Hanif, K., ... & Dwivedi, A. K. (2012). Protective effect of fruits of Morinda citrifolia L. on scopolamine induced memory impairment in mice: a behavioral, biochemical and cerebral blood flow study. Journal of ethnopharmacology, 139(1), 34-41. Full Article

NEURON PROTECTION

Harada, S., Hamabe, W., Kamiya, K., Satake, T., Yamamoto, J., & Tokuyama, S. (2009). Preventive effect of Morinda citrifolia fruit juice on neuronal damage induced by focal ischemia. Biological and Pharmaceutical Bulletin, 32(3), 405-409. Full Article

WOUND HEALING

Nayak, B. S., Sandiford, S., & Maxwell, A. (2009). Evaluation of the wound-healing activity of ethanolic extract of Morinda citrifolia L. leaf. Evidence-Based Complementary and Alternative Medicine, 6(3), 351-356. Full Article

VARIOUS PROPERTIES

Assi, R. A., Darwis, Y., Abdulbaqi, I. M., Vuanghao, L., & Laghari, M. H. (2017). Morinda citrifolia (Noni): A comprehensive review on its industrial uses, pharmacological activities, and clinical trials. Arabian Journal of Chemistry, 10(5), 691-707. Full Article

Singh, D. R. (2012). Morinda citrifolia L.(Noni): A review of the scientific validation for its nutritional and therapeutic properties. Journal of Diabetes and Endocrinology, 3(6), 77-91. Full Article

Medicinal Properties
[other journals]

Medical Conditions [other journals]

Videos

Conference Presentations

Cowden Support Program for Lyme: Observational Study – Dublin, Ireland – June, 2012 Armin Schwarzbach, MD PhD Full Video

Patient Reports

"I used it against chronic scalp lesions suspected from EBV and it definitely improved them by 80% in two weeks.  The mechanism of action is to bind with sugars in the viral envelope so I take it on an empty stomach and give it 15 minutes to work before eating anything else."-A.B.

“Hey... This stuff actually works. My family has used it all winter when attacked by the flu virus and remain pleased! Take it right away when the symptoms are first felt. It does wonders.” – V.H

“Love this stuff!!! If you haven't seen the 2 minute YouTube video you should. It wipes out viruses for us just like the video says. I keep it in stock in the house at all times.” – D.T

"LOVE this product!!! I keep this on hand at all times. If you take 30-60 drops of this in water at the onset of cold or flu, it will knock it out!!!! AWESOME RESULTS!!"-S.A.

"This stuff actually works. My family has used it all winter when attacked by the flu virus and remain pleased! Take it right away when the symptoms are first felt. It does wonders."-V.H.

Dosage Information

Acute Infections: 30 drops every hour. 

Chronic Infections: 30 drops 2-4 times daily at least 30 minutes before a meal and/or at bedtime.

Protocols

ARTHRITIS (OSTEO AND RHEUMATOID)

ATHEROSCLEROTIC DISEASE

BREAST CANCER

DIABETES (TYPE1 AND TYPE 2)

HEADACHES (SEVERE)

HEPATITIS C

HERPES (GENITAL)

MENINGITIS (VIRAL)

PROSTATE CANCER

VIRAL INFECTIONS (ACUTE-COLDS AND FLU)

Safety Information

An Acute Oral toxicity study was conducted by the Department of Chemical Sciences at the University of Guayaquil, Ecuador.  The general conclusion was that Takuna did not produce toxic effects when used in accordance to the guidelines described in OECD TG 423, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article 

Product Label

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TAKUNA
Takuna: Acute Oral Toxicity

Takuna will be used in humans because of the vital importance of carrying out these first-step tests. They will not only guarantee the quality of the product, but will also establish that there are no adverse side effects in humans who take the product. As discussed in numerous international works, the study of acute toxicity is indispensable, and guarantees (within the margin of error associated with the technique) that the potential for toxicity from the compounds that will be ingested or that may enter into the system accidentally will be learned.

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Takuna: Anti-Inflammatory Effect

The auricular edema is achieved by applying 12-0- Tetradecanoil Forbol-13 Acetate (TPA), one of the components responsible for the irritating action of croton oil, into the auditory pavilion of the mouse. The inflammatory reaction consists of erythema , edema and infiltration by polymorphonuclear leukocytes. As such, eicosanoid -type mediators are freed, inducing degranulation of the mast cell. This technique thus allows the evaluation of the inhibiting substances of the biosynthesis of prostaglandins and leukotrienes.

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