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ZINC

IMMUNE SYSTEM SUPPORT

GASTROINTESTINAL SUPPORT – GENERAL WELLNESS – IMMUNE SYSTEM SUPPORT – MINERALS

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General Description

Glucomedix Pitch Deck

NutraMedix Zinc contains bisglycinate zinc, the form of zinc that has superior bioavailability compared to zinc gluconate. NutraMedix Zinc is well tolerated, offers excellent tissue retention, and is gentle on the system.

Some Reported Medicinal Properties

ANTIDEPRESSANT

ANTI-INFLAMMATORY

ANTIVIRAL

ANTICOAGULANT

HELPS PREVENT AND TREAT RHEUMATOID ARTHRITIS

SUPPORTS WOUND HEALING

SUPPORTS IMMUNITY AND CELLULAR METABOLISM

SUPPORTS HAIR, SKIN, NAILS, AND CARTILAGE

ESSENTIAL FOR SENSES, ESPECIALLY TASTE AND SMELL

ESSENTIAL TO PRODUCTION OF OVER 300 ENZYMES

SUPPORTS THYROID FUNCTION

BOOSTS SEX HORMONES (TESTOSTERONE AND PROLACTIN)

FACILITATES FALLING ASLEEP AND RESTORATIVE SLEEP

SUPPORTS NEUROTRANSMITTER FUNCTION AND COGNITION

CALMATIVE

Research On NutraMedix Product

Antioxidant

Vavvas, D. G., Small, K. W., Awh, C. C., Zanke, B. W., Tibshirani, R. J., & Kustra, R. (2018). CFH and ARMS2 genetic risk determines progression to neovascular age-related macular degeneration after antioxidant and zinc supplementation. Proceedings of the National Academy of Sciences, 115(4), E696-E704. Full Article

Jarosz, M., Olbert, M., Wyszogrodzka, G., Młyniec, K., & Librowski, T. (2017). Antioxidant and anti-inflammatory effects of zinc. Zinc-dependent NF-κB signaling. Inflammopharmacology, 25(1), 11-24. Full Article

El-Batal, A. I., Mosalam, F. M., Ghorab, M. M., Hanora, A., & Elbarbary, A. M. (2018). Antimicrobial, antioxidant and anticancer activities of zinc nanoparticles prepared by natural polysaccharides and gamma radiation. International journal of biological macromolecules, 107, 2298-2311. Full Article

Siripireddy, B., & Mandal, B. K. (2017). Facile green synthesis of zinc oxide nanoparticles by Eucalyptus globulus and their photocatalytic and antioxidant activity. Advanced Powder Technology, 28(3), 785-797. Full Article

Zhang, C., Gao, Z., Hu, C., Zhang, J., Sun, X., Rong, C., & Jia, L. (2017). Antioxidant, antibacterial and anti-aging activities of intracellular zinc polysaccharides from Grifola frondosa SH-05. International journal of biological macromolecules, 95, 778-787. Full Article

Xu, N., Ren, Z., Zhang, J., Song, X., Gao, Z., Jing, H., ... & Jia, L. (2017). Antioxidant and anti-hyperlipidemic effects of mycelia zinc polysaccharides by Pleurotus eryngii var. tuoliensis. International journal of biological macromolecules, 95, 204-214. Full Article

Rajakumar, G., Thiruvengadam, M., Mydhili, G., Gomathi, T., & Chung, I. M. (2018). Green approach for synthesis of zinc oxide nanoparticles from Andrographis paniculata leaf extract and evaluation of their antioxidant, anti-diabetic, and anti-inflammatory activities. Bioprocess and biosystems engineering, 41(1), 21-30. Full Article

Lee, S. R. (2018). Critical role of zinc as either an antioxidant or a prooxidant in cellular systems. Oxidative medicine and cellular longevity, 2018. Full Article

Prasad, A. S., & Bao, B. (2019). Molecular mechanisms of zinc as a pro-antioxidant mediator: clinical therapeutic implications. Antioxidants, 8(6), 164. Full Article

Bioavailability

Gandia, Bour, Maurette, Donazzolo, Duchène, Béjot, & Houin. (2007). A bioavailability study comparing two oral formulations containing zinc (Zn bis-glycinate vs. Zn gluconate) after a single administration to twelve healthy female volunteers. International journal for vitamin and nutrition research, 77(4), 243-248. Full Article

DiSilvestro, R. A., Koch, E., & Rakes, L. (2015). Moderately high dose zinc Gluconate or zinc Glycinate: effects on plasma zinc and erythrocyte superoxide dismutase activities in young adult women. Biological trace element research, 168(1), 11-14. Full Article

Skin

Ogawa, Y., Kinoshita, M., Shimada, S., & Kawamura, T. (2018). Zinc and skin disorders. Nutrients, 10(2), 199. Full Article

Immune Support

Wessels, I., Maywald, M., & Rink, L. (2017). Zinc as a gatekeeper of immune function. Nutrients, 9(12), 1286. Full Article

Medical Conditions [peer-reviewed journals]

Medicinal Properties [peer-reviewed journals]

Medicinal Properties
[other journals]

Medical Conditions [other journals]

Videos

Conference Presentations

Patient Reports

Dosage Information

Protocols

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ZINC
Zinc - Skin

The skin is the third most zinc (Zn)-abundant tissue in the body. The skin consists of the epidermis, dermis, and subcutaneous tissue, and each fraction is composed of various types of cells. Firstly, we review the physiological functions of Zn and Zn transporters in these cells.

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Zinc - Immune

After the discovery of zinc deficiency in the 1960s, it soon became clear that zinc is essential for the function of the immune system. Zinc ions are involved in regulating intracellular signaling pathways in innate and adaptive immune cells. Zinc homeostasis is largely controlled via the expression and action of zinc “importers” (ZIP 1–14), zinc “exporters” (ZnT 1–10), and zinc-binding proteins.

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Zinc - Bioavailability (superoxide)

Some zinc (Zn) research studies have used either Zn gluconate or Zn glycinate, but the two forms have not been compared much. Therefore, a moderately high dose of the two forms (60 mg Zn/day) were compared in a 6-week intervention in young adult women.

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Zinc - Antioxidant (therapeutic)

The essentiality of zinc as a trace mineral in human health has been recognized for over five decades. Zinc deficiency, caused by diet, genetic defects, or diseases, can cause growth retardation, delayed sexual maturation, depressed immune response, and abnormal cognitive functions in humans. Zinc supplementation in zinc-deficient individuals can overcome or attenuate these abnormalities, suggesting zinc is an essential micro-nutrient in the body.

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Zinc - Antioxidant (prooxidant)

Zinc is recognized as an essential trace metal required for human health; its deficiency is strongly associated with neuronal and immune system defects. Although zinc is a redox-inert metal, it functions as an antioxidant through the catalytic action of copper/zinc-superoxide dismutase, stabilization of membrane structure, protection of the protein sulfhydryl groups, and upregulation of the expression of metallothionein, which possesses a metal-binding capacity and also exhibits antioxidant functions.

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Zinc - Antioxidant (nanoparticles)

Bio-mediated synthesis of zinc oxide nanoparticles (ZnO NPs) was carried out by utilizing the reducing and capping potential of Andrographis paniculata leaf extract.

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Zinc - Antioxidant (mycelia)

The aims of this work were designed to investigate the hepatoprotective and antioxidant effects of acidic- and alkali-extractable mycelia zinc polysaccharides (AcMZPS, AlMZPS) from Pleurotus eryngii var.tuoliensis on high-fat-high-cholesterol emulsion-induced hyperlipidemic mice.

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Zinc - Antioxidant (grifola)

In present work, the strain of Grifola frondosa SH-05 was used as a vector of zinc biotransformation to produce the IZPS. The bioactivities including antioxidant and antibacterial activities in vitro and antiaging properties in vivo of IZPS were investigated comparing with the IPS.

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Zinc - Antioxidant (green)

Eucalyptus globulus leaf extract mediated synthesis of spherical zinc oxide nanoparticles (ZnO NPs) was carried out under ambient conditions. UV–Visible studies of the synthesized nanoparticles revealed the characteristic peak at 361 nm indicating the formation of ZnO nanoparticles.

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Zinc - Antioxidant (gamma)

Aqueous dispersed zinc nanoparticles (ZnNPs) were synthesized using natural polysaccherides (chitosan (CS), citrus pectin (CP) and alginate (Alg)) using aqueous fermented fenugreek powder (FFP) by Pleurotus ostreatus as reducing and stabilizing agent or using gamma irradiation. The synthesized ZnNPs are characterized by ultra violect spectroscopy (UV), Transmission electron microscopy (TEM), Dynamic light scattering (DLS), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR). XRD analysis of the ZnNPS confirmed the formation of metallic nanoparticles.

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Zinc - Antioxidant (dependent)

Zinc is a nutritionally fundamental trace element, essential to the structure and function of numerous macromolecules, including enzymes regulating cellular processes and cellular signaling pathways. The mineral modulates immune response and exhibits antioxidant and anti-inflammatory activity. Zinc retards oxidative processes on a long-term basis by inducing the expression of metallothioneins.

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Zinc - Antioxidant (CFH)

We evaluated the influence of an antioxidant and zinc nutritional supplement [the Age-Related Eye Disease Study (AREDS) formulation] on delaying or preventing progression to neovascular AMD (NV) in persons with age-related macular degeneration (AMD).

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