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HOUTTUYNIA

MICROBIAL DEFENSE

TO RESOLVE:

  • VIRAL INFECTIONS (ACUTE AND CHRONIC)
  • BACTERIAL INFECTIONS (ACUTE AND CHRONIC)

General Description

Houttuynia is an extract of the leaves of Houttuynia cordata.  Houttuynia cordata is a Chinese medicinal herb that is found throughout Eastern Asia.  It has been used traditionally to treat various types of infections, inflammation, hypertension, sinusitis, pulmonary tuberculosis, etc.  Dr. James Schaller has found Houttuynia to be effective against Bartonella in vitro and in vivo and Dr. Lee Cowden has found Houttuynia to be effective against Bartonella clinically in patients who have resistant strains of Bartonella.

Some Reported Medicinal Properties

ANTI-BACTERIAL

ANTI-VIRAL

IMMUNOMODULATION

ANTI-OXIDANT

ANTI-MUTAGENIC

Reasearch On Nutramedix Product

In vitro – Lyme Disease

Priyanka A.S. Theophilus M.S., Eva Sapi Ph.D. (2013). Study of the acute oral toxicity of HOUTTUYNIA, originating from NUTRAMEDIX Laboratories, LLC, Florida, USA.l Agents on Borrelia burgdorferi Full Article

IN VIvO ACCUTE ORAL TOXICITY TESTS

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Houttuynia did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article

Medical Conditions [peer-reviewed journals]

ACNE

Chomnawang, M. T., Surassmo, S., Nukoolkarn, V. S., & Gritsanapan, W. (2005). Antimicrobial effects of Thai medicinal plants against acne-inducing bacteria. Journal of Ethnopharmacology, 101(1-3), 330-333. Full Article

Anaphylactic Reaction

Han, E. H., Park, J. H., Kim, J. Y., & Jeong, H. G. (2009). Houttuynia cordata water extract suppresses anaphylactic reaction and IgE-mediated allergic response by inhibiting multiple steps of FcεRI signaling in mast cells. Food and Chemical Toxicology, 47(7), 1659-1666. Full Article

Li, G. Z., Chai, O. H., Lee, M. S., Han, E. H., Kim, H. T., & Song, C. H. (2005). Inhibitory effects of Houttuynia cordata water extracts on anaphylactic reaction and mast cell activation. Biological and Pharmaceutical Bulletin, 28(10), 1864-1868. Full Article

Alzheimer’s disease

Huh, E., Kim, H. G., Park, H., Kang, M. S., Lee, B., & Oh, M. S. (2014). Houttuynia cordata improves cognitive deficits in cholinergic dysfunction Alzheimer’s disease-like models. Biomolecules & Therapeutics, 22(3), 176. Full Article

CANCER

Kumnerdkhonkaen, P., Saenglee, S., Asgar, M. A., Senawong, G., Khongsukwiwat, K., & Senawong, T. (2018). Antiproliferative activities and phenolic acid content of water and ethanolic extracts of the powdered formula of Houttuynia cordata Thunb. fermented broth and Phyllanthus emblica Linn. fruit. BMC Complementary and Alternative Medicine, 18(1), 130. Full Article

Lai, K. C., Chiu, Y. J., Tang, Y. J., Lin, K. L., Chiang, J. H., Jiang, Y. L., ... & Yang, J. S. (2010). Houttuynia cordata Thunb extract inhibits cell growth and induces apoptosis in human primary colorectal cancer cells. Anticancer Research, 30(9), 3549-3556. Full Article

COLON CANCER

Tang, Y. J., Yang, J. S., Lin, C. F., Shyu, W. C., Tsuzuki, M., Lu, C. C., ... & Lai, K. C. (2009). Houttuynia cordata Thunb extract induces apoptosis through mitochondrial-dependent pathway in HT-29 human colon adenocarcinoma cells. Oncology Reports, 22(5), 1051-1056. Full Article

Dengue Virus

Chiow, K. H., Phoon, M. C., Putti, T., Tan, B. K., & Chow, V. T. (2016). Evaluation of antiviral activities of Houttuynia cordata Thunb. extract, quercetin, quercetrin and cinanserin on murine coronavirus and dengue virus infection. Asian Pacific Journal of Tropical Medicine, 9(1), 1-7. Full Article

Leardkamolkarn, V., Sirigulpanit, W., Phurimsak, C., Kumkate, S., Himakoun, L., & Sripanidkulchai, B. (2012). The inhibitory actions of houttuynia cordata aqueous extract on dengue virus and dengue‐infected cells. Journal of Food Biochemistry, 36(1), 86-92. Full Article

Diabetes

Kumar, M., Prasad, S. K., Krishnamurthy, S., & Hemalatha, S. (2014). Antihyperglycemic activity of Houttuynia cordata Thunb. in streptozotocin-induced diabetic rats. Advances in Pharmacological Sciences, 2014. Full Article

Leukemia

Chang, J. S., Chiang, L. C., Chen, C. C., Liu, L. T., Wang, K. C., & Lin, C. C. (2001). Antileukemic activity of Bidens pilosa L. var. minor (Blume) Sherff and Houttuynia cordata Thunb. The American Journal of Chinese Medicine, 29(02), 303-312. Full Article

LUNG CANCER

Chen, Y. F., Yang, J. S., Chang, W. S., Tsai, S. C., Peng, S. F., & Zhou, Y. R. (2013). Houttuynia cordata Thunb extract modulates G 0/G 1 arrest and Fas/CD95-mediated death receptor apoptotic cell death in human lung cancer A549 cells. Journal of Biomedical Science, 20(1), 18. Full Article

Lung Injury

Lu, Y., Jiang, Y., Ling, L., Zhang, Y., Li, H., & Chen, D. (2018). Beneficial effects of Houttuynia cordata polysaccharides on “two-hit” acute lung injury and endotoxic fever in rats associated with anti-complementary activities. Acta Pharmaceutica Sinica B, 8(2), 218-227. Full Article

Herpes Simplex Virus (HSV)        

Hung, P. Y., Ho, B. C., Lee, S. Y., Chang, S. Y., Kao, C. L., Lee, S. S., & Lee, C. N. (2015). Houttuynia cordata targets the beginning stage of herpes simplex virus infection. PloS One, 10(2), e0115475. Full Article

Chen, X., Wang, Z., Yang, Z., Wang, J., Xu, Y., Tan, R. X., & Li, E. (2011). Houttuynia cordata blocks HSV infection through inhibition of NF-κB activation. Antiviral Research, 92(2), 341-345. Full Article

Chiang, L. C., Chang, J. S., Chen, C. C., Ng, L. T., & Lin, C. C. (2003). Anti-Herpes simplex virus activity of Bidens pilosa and Houttuynia cordata. The American Journal of Chinese Medicine, 31(03), 355-362. Full Article

Rapid pulmonary fibrosis (RPF)

Du, S., Li, H., Cui, Y., Yang, L., Wu, J., Huang, H., ... & Chen, D. (2012). Houttuynia cordata inhibits lipopolysaccharide-induced rapid pulmonary fibrosis by up-regulating IFN-γ and inhibiting the TGF-β1/Smad pathway. International Immunopharmacology, 13(3), 331-340. Full Article

Medicinal Properties [peer-reviewed journals]

Anticestodal activity

Yadav, A. K. (2011). Anticestodal activity of Houttuynia cordata leaf extract against Hymenolepis diminuta in experimentally infected rats. Journal of Parasitic Diseases, 35(2), 190-194. Full Article

Anti-inflammatory

Shingnaisui, K., Dey, T., Manna, P., & Kalita, J. (2018). Therapeutic potentials of Houttuynia cordata Thunb. against inflammation and oxidative stress: A Review. Journal of Ethnopharmacology. Full Article

Li, W., Fan, T., Zhang, Y., Fan, T., Zhou, P., Niu, X., & He, L. (2013). Houttuynia cordata Thunb. Volatile Oil Exhibited Anti‐inflammatory Effects In Vivo and Inhibited Nitric Oxide and Tumor Necrosis Factor‐α Production in LPS‐stimulated Mouse Peritoneal Macrophages In Vitro. Phytotherapy Research, 27(11), 1629-1639. Full Article

Lee, H. J., Seo, H. S., Kim, G. J., Jeon, C. Y., Park, J. H., Jang, B. H., ... & Ko, S. G. (2013). Houttuynia cordata Thunb inhibits the production of proinflammatory cytokines through inhibition of the NFκB signaling pathway in HMC1 human mast cells. Molecular Medicine Reports, 8(3), 731-736. Full Article

Kim, D., Park, D., Kyung, J., Yang, Y. H., Choi, E. K., Lee, Y. B., ... & Kim, Y. B. (2012). Anti-inflammatory effects of Houttuynia cordata supercritical extract in carrageenan-air pouch inflammation model. Laboratory Animal Research, 28(2), 137-140. Full Article

Li, W., Zhou, P., Zhang, Y., & He, L. (2011). Houttuynia cordata, a novel and selective COX-2 inhibitor with anti-inflammatory activity. Journal of Ethnopharmacology, 133(2), 922-927. Full Article

Shin, S., Joo, S. S., Jeon, J. H., Park, D., Jang, M. J., Kim, T. O., ... & Kim, Y. B. (2010). Anti-inflammatory effects of a Houttuynia cordata supercritical extract. Journal of Veterinary Science, 11(3), 273-275. Full Article

Kim, I. S., Kim, J. H., Kim, J. S., Yun, C. Y., Kim, D. H., & Lee, J. S. (2007). The inhibitory effect of Houttuynia cordata extract on stem cell factor-induced HMC-1 cell migration. Journal of Ethnopharmacology, 112(1), 90-95. Full Article

Lu, H. M., Liang, Y. Z., Yi, L. Z., & Wu, X. J. (2006). Anti-inflammatory effect of Houttuynia cordata injection. Journal of Ethnopharmacology, 104(1-2), 245-249. Full Article

Antibacterial

Li, W., Zhou, P., Zhang, Y., & He, L. (2011). Houttuynia cordata, a novel and selective COX-2 inhibitor with anti-inflammatory activity. Journal of Ethnopharmacology, 133(2), 922-927. Full Article

Kim, G. S., Kim, D. H., Lim, J. J., Lee, J. J., Han, D. Y., Lee, W. M., ... & Lee, H. J. (2008). Biological and antibacterial activities of the natural herb Houttuynia cordata water extract against the intracellular bacterial pathogen salmonella within the RAW 264.7 macrophage. Biological and Pharmaceutical Bulletin, 31(11), 2012-2017. Full Article

Antioxidant

Tian, L., Shi, X., Yu, L., Zhu, J., Ma, R., & Yang, X. (2012). Chemical composition and hepatoprotective effects of polyphenol-rich extract from Houttuynia cordata tea. Journal of Agricultural and Food Chemistry, 60(18), 4641-4648. Full Article

Tian, L., Zhao, Y., Guo, C., & Yang, X. (2011). A comparative study on the antioxidant activities of an acidic polysaccharide and various solvent extracts derived from herbal Houttuynia cordata. Carbohydrate Polymers, 83(2), 537-544. Full Article

Nuengchamnong, N., Krittasilp, K., & Ingkaninan, K. (2009). Rapid screening and identification of antioxidants in aqueous extracts of Houttuynia cordata using LC–ESI–MS coupled with DPPH assay. Food Chemistry, 117(4), 750-756. Full Article

Chen, Y. Y., LIU, T. F., Chen, C. M., Chao, P. Y., & Chang, T. J. (2003). A study of the antioxidative and antimutagenic effects of Houttuynia cordata Thunb. using an oxidized frying oil-fed model. Journal of Nutritional Science and Vitaminology, 49(5), 327-333. Full Article

Anti-Obesity

Miyata, M., Koyama, T., & Yazawa, K. (2010). Water extract of Houttuynia cordata Thunb. leaves exerts anti-obesity effects by inhibiting fatty acid and glycerol absorption. Journal of Nutritional Science and Vitaminology, 56(2), 150-156. Full Article

Hepatoprotector

Chen, W. T., Yang, C. L., & Yin, M. C. (2014). Protective effects from Houttuynia cordata aqueous extract against acetaminophen-induced liver injury. Biomedicine, 4(1). Full Article

Immunomodulating

Lee, J. S., Kim, I. S., Kim, J. H., Kim, J. S., Kim, D. H., & Yun, C. Y. (2008). Suppressive effects of Houttuynia cordata Thunb (Saururaceae) extract on Th2 immune response. Journal of Ethnopharmacology, 117(1), 34-40. Full Article

Lau, K. M., Lee, K. M., Koon, C. M., Cheung, C. S. F., Lau, C. P., Ho, H. M., ... & Tsui, S. K. W. (2008). Immunomodulatory and anti-SARS activities of Houttuynia cordata. Journal of Ethnopharmacology, 118(1), 79-85. Full Article

Medicinal Properties
[other journals]

Medical Conditions [other journals]

LYME DISEASE

Why this Finnish Doctor Believes in Herbs, Marjo Valonen MD, Townsend Letter, July 2018 Full Article   

A Hidden Epidemic: Integrative Treatment of Lyme Disease, Scott Forsgren, March 2009 Full Article

Videos

Conference Presentations

Cowden Support Program for Lyme: Observational Study – Dublin, Ireland – June, 2012 Armin Schwarzbach, MD PhD Full Video

Patient Reports

"Houttuynia Microbial Defense by NutraMedix helps my chronic mono when it flares up." -C.H.

“This is a lot better than other brands of Houttuynia on the market. It's a night and day difference for me… “ – F.L.

“I've been fighting Lyme with Bartonella and Babesia. This product seems to make a difference in my overall health and comfort when antibiotics failed. This is staying in my arsenal of weapons!” – J.R

“Alas, nothing I have done RIDS me of my chronic Mono...but Houttuynia Microbial Defense by NutraMedix helps when it flares up.” –R.N.

"This product was recommended for mycoplasma. It really was a slam dunk for my child and made and is making a huge difference in his recovery from it as well as from digestive distress from chronic food sensitivities and allergies. I can't recommend it enough for those with these issues." –N.P

Dosage Information

30 drops twice daily at least 30 minutes before a meal (start with 1 drop in 4 oz. of water adding a drop with each dose).

Protocols

Safety Information

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Houttuynia did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article

Product Label

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HOUTTUYNIA
Houttuynia: Toxicity Study (English Translated)

HOUTTUYNIA will be used in humans because of the vital importance of carrying out these first-step tests. They will not only guarantee the quality of the product, but will also establish that there are no adverse side effects in humans who take the product.

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Houttuynia: rapid pulmonary fibrosis (RPF)

Traditionally, acute lung injury (ALI) causes pneumonedema and matrix lesions, rather than pulmonary fibrosis.

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Houttuynia: Lung Injury

Houttuynia cordata Thunb. is a traditional herb used for clearing heat and eliminating toxins, and has also been used for the treatment of severe acute respiratory syndrome (SARS).

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Houttuynia: Lung Cancer

In Taiwan, 26 individuals per 100,000 died from lung cancer each year, based on reports from the “People Health Bureau of Taiwan”. Surgery, radiotherapy, and chemo-therapy are used for treating lung cancer patients.

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Houttuynia: Leukemia

During the past fifty years, there had been a great deal of interest in screening therapeutic agents from plants. Bidens pilosa L. is widely used in traditional medicine for anti­influenza, diabetic control and treatment of gastroenteritis.

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Houttuynia: Immunomodulating

Houttuynia cordata Thunb. (Saururaceae) (HC) is a traditional Chinese medicine (TCM) used for hundreds of year to relieve lung-related symptoms such as lung abscess, phlegm, cough and dyspnea and is effective in treating pneumonia, infectious disease, refractory hemoptysis as well as malignant pleural effusion. Recently, several studies also provided scientific data to sup-port and unveil its anti-inflammatory, anti-allergic, virucidal, anti-oxidative and anti-cancer activities.

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Houttuynia: Immunomodulating (Th2)

Houttuynia cordata Thunb (Saururaceae), known as ‘E-Sung-Cho’ in Korea, has been traditionally used for the treatment of herpes simplex, chronic sinusitis, and allergy.

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Houttuynia: HSV

Houttuynia cordata Thunb. is a medicinal plant widely used in folk medicine in several Asian countries. It has been reported that a water extract of H. cordata exhibits activity against herpes simplex virus (HSV) and the virus of severe acute respiratory syndrome (SARS), although the mechanisms are not fully under-stood yet.

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Houttuynia: HSV (Biden)

During the past 50 years, a great deal of interest had been initiated in screening therapeutic agents from plants. Bidens pilosa L. was widely used as a traditional remedy for treating influenza, diabetes and gastroenteritis worldwide.

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Houttuynia: HSV (Beginning)

Herpes simplex virus (HSV), a common latent virus in humans, causes certain severe dis-eases. Extensive use of acyclovir (ACV) results in the development of drug-resistant HSV strains, hence, there is an urgent need to develop new drugs to treat HSV infection.

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Houttuynia: hepatoprotector (acetaminophen)

Protective effects of Houttuynia cordata aqueous extract (HCAE) against acetaminophen-induced hepatotoxicity in Balb/cA mice were examined.

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Houttuynia: GIT

This study was conducted to investigate the effects of the medicinal plant yarrow (Achillea millefolium L.), a probiotic (Primalac) and an antibiotic (virginiamycin) on gastrointestinal tract (GIT) characteristics, microbial populations, immune response, serum lipids and growth performance of broiler chickens.

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Houttuynia: Diabetes

Present study is an attempt to investigate plausible mechanism involved behind antidiabetic activity of standardized Houttuynia cordata Thunb. extract in streptozotocin-induced diabetic rats.

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Houttuynia: Dengue Virus (Evaluation)

To evaluate the in vitro activities of the ethyl acetate (EA) fraction of Houttuynia cordata (H. cordata) Thunb. (Saururaceae) and three of its constituent fla-vonoids (quercetin, quercitrin and rutin) against murine coronavirus and dengue virus (DENV).

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Houttuynia: Colon Cancer

The Houttuynia cordata Thunb (HCT) extract has been used as a traditional Chinese herb medicine and as well as an effective drug for treating allergic inflammation for thousands of years.

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Houttuynia: Cancer

Colorectal cancer (CRC) is one of the most prevalent types of cancer worldwide and a common cause of morbidity and mortality in humans.

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Houttuynia: Cancer (Powder)

Nowadays, cancer is the leading cause of death in many countries of the world. Chemotherapy is a common treatment strategy for advanced and metastatic cancer. However, the cost of chemotherapy is a major concern in developing countries.

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Houttuynia: Antiviral (Dengue)

Houttuynia cordata Thunb (Saururaceae; H. cordata)com-monly known as “Pak Kan Thong” in Thai, is a popular side-dish vegetable, which is consumed in the Northern and Eastern regions of Thailand.

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Houttuynia: Antispasmodic

Achillea millefolium L. is cultivated in Iran and widely used in traditional medicine for gastrointestinal disorders. The aim of this study was to determine the effect of hydroalcoholic extract of A. millefolium on the contraction and relaxation of isolated ileum in rat.

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Houttuynia: Antioxidant

This study is designed to compare the antioxidant potential of a water-soluble polysaccharide (HCP) with solvent extracts (water, ethanol, ethyl acetate and chloroform) from Houttuynia cordata Thunb.

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Houttuynia: Antioxidant (Tea)

The liver plays a pivotal role in metabolism and detoxification of various components entering the body, and hepatic injury associated with these metabolic dysfunctions can result in many disorders ranging from transient elevation of liver enzymes to life-threatening hepatic fibrosis, liver cirrhosis, and even hepatocellular carcinoma.

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Houttuynia: Antioxidant (Rapid)

Houttuynia cordata Thunb. has been used traditionally as immune stimulant and anticancer agent. An aqueous extract of H. cordata tea showed high radical scavenging activity determined by off-line DPPH assays.

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Houttuynia: Antioxidant (nitrogen)

In this study, the effects of long-term nitrogen deficiency (N 0.1 mM for 4 months) on growth, phenolic content and activity of phenylalanine ammonia lyase (PAL; EC 4.3.1.5) were investigated in the leaves, inflorescences and roots of yarrow (Achillea collina Becker ex Rchb.) grown in hydroponics.

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Houttuynia: Antioxidant (Frying)

The aims of this study were to evaluate the antioxidative effect of a traditional Taiwanese vegetable, Houttuynia cordata Thunb. (H. cordata), by subjecting rodents to oxi­dized frying oil-induced oxidative stress, and to examine the antimutagenic effects of H. car­data using the Ames test.

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Houttuynia: Anti-obesity

Houttuynia cordata Thunb. is used in folk medicine for diuresis and detoxifica-tion. However, it has not yet been reported to have an anti-obesity effect.

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Houttuynia - Anti-inflammatory (supercritical)

Traditionally, Houttuynia (H.) cordata Thunb has been used as an Oriental medicine for the treatment of inflam­matory diseases such as ulcerative colitis. Previous studies showed that H. cordata extracts had antiviral and antibacterial, antiallergic, antioxidant and antimutagenic activities.

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Houttuynia: Anti-inflammatory (stem cell)

Hottuynia cordata Thunb (Saururaceae; HC) is known as a therapeutic drug that has been used in traditional oriental medicine for the treatment of allergy. Mast cells play an important role in a variety of inflammatory diseases, and specifically asthma and atopy. In the present study, we investigated the effect of HC extracts on the migration of the human mast cell line, HMC-1, in response to stem cell factor (SCF).

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Houttuynia: Anti-inflammatory (pouch)

It has been reported that Houttuynia (H.) cordata extracts have diverse pharmacological effects including antiviral and antibacterial, antiallergic, antioxidant and antimutagenic activities. Thus, H. cordata Thunb has been used as an Oriental medicine for the therapy of inflammatory diseases such as ulcerative colitis.

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Houttuynia: Anti-inflammatory (potentials)

Houttuynia cordata Thunb. (Family: Saururaceae) is an herbaceous perennial plant that grows in moist and shady places. The plant is well known among the people of diverse cultures across Japan, Korea, China and North-East India for its medicinal properties. Traditionally the plant is used for its various beneficial properties against inflammation, pneumonia, severe acute respiratory syndrome, muscular sprain, stomach ulcer etc.

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Houttuynia: Anti-inflammatory (Necrosis F)

Houttuynia cordata Thunb. (HC) is a medicinal herb that generally used in traditional Chinese medicine for treat-ing allergic inflammation. The present study investigated the inhibitory effect of the volatile oil from HC Thunb.

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Houttuynia: Anti-inflammatory (injection)

Houttuynia cordata (Saururaceae) injection (HCI) is a traditional Chinese medicine used in China. It was chosen as one of eight types of traditional Chinese medicine that play a unique role in severe acute respiratory syndrome (SARS) owing to the effect of curbing inflammation.

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Houttuynia: Anti-inflammatory (HMC-1)

Houttuynia cordata Thunb (HCT) is widely used in oriental medicine as a remedy for inflammation. However, at present there is no explanation for the mechanism by which HCT affects the production of inflammatory cytokines. The current study aimed to determine the effect of an essence extracted from HCT on mast cell-mediated inflammatory responses.

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Houttuynia: Anti-inflammatory (COX)

Houttuynia cordata Thunb. (Saururaceae; HC) has been long used in tra-ditional oriental medicine for the treatment of inflammation diseases. Modern research has implicated inducible cyclooxygenase-2 (COX-2) as a key regulator of the inflammatory process.

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Houttuynia: Anticestodal activity

The leaves of Houttuynia cordata Thunb.(Saururaceae) are considered to have anthelmintic proper-ties in the traditional medicine of Naga tribes in Northeast India and, therefore, are used by the natives to treat the intestinal worm infections. In the present study, the anti-cestodal activity of H. cordata leaf extract was investigated against Hymenolepis diminuta, a zoonotic cestode, in experimentally infected albino rats.

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Houttuynia: Antibacterial

Houttuynia cordata Thunb. (Saururaceae; HC) has been long used in tra-ditional oriental medicine for the treatment of inflammation diseases. Modern research has implicated inducible cyclooxygenase-2 (COX-2) as a key regulator of the inflammatory process.

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Houttuynia: Antibacterial (RAW)

Salmonellosis is a major bacterial zoonosis that causes a variety of disease syndromes, from self-limiting enteritis to fatal infection in animals and food-borne infection and typhoid fever in humans.

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Houttuynia: Anaphylatic Reaction

The present study was investigated the effect of Houttuynia cordata THUNB water extract (HCWE) on mast cell-mediated anaphylactic reactions. The mast cell-mediated anaphylactic reaction is involved in many allergic diseases such as asthma and allergic rhinitis. HCWE has been used as a traditional medicine in Korea and is known to have an antioxidant and anti-cancer activities.

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Houttuynia: Anaphylatic Reaction (IgE)

Houttuynia cordata has been used as a traditional medicine in Korea and is known to have antioxidant, anti-cancer and anti-allergic activities. The precise effect of H. cordata, however, remains unknown. In this study, we investigated the effects of H. cordata water extract (HCWE) on passive cutaneous anaphy-laxis (PCA) in mice and on IgE-mediated allergic response in rat mast RBL-2H3 cells.

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Houttuynia: Alzhiemers

Cognitive impairment is a result of dementia of diverse causes, such as cholinergic dysfunction and Alzheimer’s disease (AD). Houttuynia cordata Thunb. (Saururaceae) has long been used as a traditional herbal medicine. It has biological activities including protective effects against amyloid beta (Aβ) toxicity, via regulation of calcium homeostasis, in rat hippocampal cells.

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Houttuynia: Acne

Propionibacterium acnes and Staphylococcus epidermidis have been recognized as pus-forming bacteria triggering an inflammation in acne. The present study was conducted to evaluate antimicrobial activities of Thai medicinal plants against these etiologic agents of acne vulgaris.

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