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TEASEL

MICROBIAL DEFENSE

• DIURETIC

• ANTI-FUNGAL

• ANTI-OSTEOPOROTIC

• CHRONIC BORRELIOSIS

• LIVER CLEANSE

• MOOD DISORDERS

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General Description

Teasel is an extract produced from the root of Dipsacus fullonum, a wild flowering plant found in moderate climates around the world.  It is known as a common adjunct to fighting chronic Lyme Disease and has many other medicinal properties.  Teasel increases circulation and pulls toxins (including bacteria and fungi) from the tissues of the body, which allows anti-microbial agents to destroy the pathogens.  The diuretic properties of Teasel support the liver to rid the body of liver toxicity.  It will also assist in detoxifying the body in the event of a Herxheimer reaction.

Some Reported Medicinal Properties

ANTIFUNGAL

ANTIOSTEOPOROTIC

DIURETIC

DETOXIFIER

ANTIDEPRESSIVE

Research On NutraMedix Product

Medical Conditions [peer-reviewed journals]

BLADDER CANCER

Dietrich, F., Kaiser,S., Rockenbach, L., Figueiró, F., Bergamin, L. S., da Cunha, F. M., ... &Battastini, A. M. O. (2014). Quinovicacid glycosides purified fraction from Uncaria tomentosa induces cell death byapoptosis in the T24 human bladder cancer cell line. Food and Chemical Toxicology67, 222-229. Full Article

BRAIN CANCER

Prado, E. G., Gimenez,M. G., De la Puerta Vázquez, R., Sánchez, J. E., & Rodriguez, M. S. (2007). Antiproliferative effects ofmitraphylline, a pentacyclic oxindole alkaloid of Uncaria tomentosa on humanglioma and neuroblastoma cell linesPhytomedicine, 14(4),280-284. Full Article

BREAST CANCER

Baraya, Y. U. S. A. B.,Wong, K. K., & Yaacob, N. S. (2017). The immunomodulatory potential of selected bioactive plant-based compounds in breast cancer: a review. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents), 17(6), 770-783. Full Article

García Giménez, M. D., García Prado, E., Sáenz Rodríguez, M. T., Fernández Arche, M. D. L. Á., & Puerta Vázquez-Zafra, R. D. L. (2010). Cytotoxic effect of the pentacyclic oxindole alkaloid mitraphylline isolated from Uncaria tomentosa bark on human Ewing's sarcoma and breast cancer cell lines. Planta Medica, 76, 133-136. Full Article

Riva, L., Coradini, D., Di, G. F., De, V. F., De, N. T., De, F. S., & Pizza, C. (2001). The antiproliferative effects of Uncaria tomentosa extracts and fractions on the growth of breast cancer cell line. Anticancer Research, 21(4A), 2457-2461. Full Article

CYSTITIS

Dietrich, F., Martins,J. P., Kaiser, S., Silva, R. B. M., Rockenbach, L., Edelweiss, M. I. A., ...& Battastini, A. M. O. (2015). The quinovic acid glycosides purified fraction from Uncaria tomentosa protects against hemorrhagic cystitis induced by cyclophosphamide in micePloS one, 10(7), e0131882. Full Article

DENGUE FEVER

Reis, S. R. I., Valente,L. M., Sampaio, A. L., Siani, A. C., Gandini, M., Azeredo, E. L., ... &Kubelka, C. F. (2008). Immunomodulating and antiviralactivities of Uncaria tomentosa on human monocytes infected with Dengue Virus-2International Immunopharmacology,8(3), 468-476. Full Article

DENTURE STOMATITIS

Tay, L. Y., Dos Santos,F. A., & Jorge, J. H. (2015). Uncaria tomentosa gel against denture stomatitis: clinical reportJournal of Prosthodontics,24(7), 594-597. Full Article

ENDOMETRIOSIS

Neto, J. N., Coelho, T.M., Aguiar, G. C., Carvalho, L. R., de Araújo, A. G. P., Girão, M. J. B., & Schor, E. (2011). Experimental endometriosis reduction in rats treated with Uncaria tomentosa (cat's claw)extractEuropean Journal of Obstetrics and Gynecology and Reproductive Biology, 154(2), 205-208. Full Article

HERPES

Caon, T., Kaiser, S.,Feltrin, C., de Carvalho, A., Sincero, T. C. M., Ortega, G. G., & Simões,C. M. O. (2014). Antimutagenic and antiherpetic activities of different preparations from Uncaria tomentosa (cat’s claw). Food and Chemical Toxicology, 66, 30-35. Full Article

Hypertension

Araujo, L. C., Feitosa, K.B., Murata, G. M., Furigo, I. C., Teixeira, S. A., Lucena, C. F., ... & Bordin, S. (2018). Uncaria tomentosa improves insulin sensitivity and inflammation in experimental NAFLDScientific reports, 8(1), 11013. Full Article

Zhang, Q., Zhao, J. J., Xu,J., Feng, F., & Qu, W. (2015). Medicinal uses, phytochemistry and pharmacology of the genus Uncaria. Journal of Ethnopharmacology173, 48-80. Full Article

Hao, P. P., Jiang, F., Chen,Y. G., Yang, J., Zhang, K., Zhang, M. X., ... & Zhang, Y. (2015). Traditional Chinese medication for cardiovascular diseaseNature Reviews Cardiology, 12(2), 115. Full Article

Ranilla, L. G., Kwon, Y.I., Apostolidis, E., & Shetty, K. (2010). Phenolic compounds, antioxidant activity and in vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of commonly used medicinal plants, herbs and spices in Latin AmericaBioresource technology, 101(12), 4676-4689. Full Article

Immune-mediated diseases (diabetes)                   

Layanne C C Arauj, Isadora C Furig, Gilson M Murata, J Donato Jr, Silvana Bordin, Rui Curi & Carla R O Carvalho (2017). The insulin resistance induced by obesity is reversed by Uncaria tomentosa through modulation of inflammatory pathway in the liver of mice. Journal of Diabetes and medicine, 8(10). Full Article

Domingues, A., Sartori, A., Golim, M. A., Valente, L. M. M., da Rosa, L. C., Ishikawa, L. L. W., ...& Viero, R. M. (2011). Prevention of experimental diabetes by Uncaria tomentosa extract: Th2 polarization, regulatory T cell preservation or both?Journal of Ethnopharmacology, 137(1), 635-642. Full Article

Yessoufou,A., Gbenou, J., Grissa, O., Hichami, A., Simonin, A. M., Tabka, Z., ... & Khan, N. A. (2013). Anti-hyperglycemic effects of three medicinal plants in diabetic pregnancy: modulation of T cell proliferationBMC complementary and alternative medicine, 13(1), 77. Full Article

Araujo, L. C., Feitosa,K. B., Murata, G. M., Furigo, I. C., Teixeira, S. A., Lucena, C. F., ... &Bordin, S. (2018). Uncaria tomentosa improves insulin sensitivity and inflammation in experimental NAFLDScientific reports, 8(1),11013. Full Article

Mahmoudian-Sani,M., Luther, T., Asadi-Samani, M., Saeedi-Boroujeni, A., & Gholamian, N.(2017). A new approach for treatment of type 1 diabetes: Phytotherapy and phytopharmacology of regulatory T cellsJ Renal Inj Prev, 6(3),158-63. Full Article

Pane,Y. S., Ganie, R. A., Lindarto, D., & Lelo, A. (2018). The Effect of Gambier Extract on the Levels of Malondialdehyde, Superoxide Dismutase, and Blood Glucose in Type 2 Diabetes Mellitus PatientsAsian J Pharm Clin Res,11(10), 121-124. Full Article

LEUKEMIA

Pilarski, R.,Poczekaj-Kostrzewska, M., Ciesiolka, D., Szyfter, K., & Gulewicz, K.(2007). Antiproliferative activity of various Uncaria tomentosa preparations on HL-60 promyelocytic leukemia cells. Pharmacological reports,59(5), 565. Full Article

LISTERIA

Eberlin, S., dos Santos,L. M., & Queiroz, M. L. (2005). Uncaria tomentosa extract increases the number of myeloid progenitor cells in the bone marrow of mice infected with Listeria monocytogenes. International Immunopharmacology, 5(7-8), 1235-1246. Full Article

Osteoarthritis

Piscoya, J., Rodriguez,Z., Bustamante, S. A., Okuhama, N. N., Miller, M. J. S., & Sandoval, M.(2001). Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis. Inflammation Research, 50(9), 442-448. Full Article

Rheumatoid Arthritis

Mur, E., Hartig, F.,Eibl, G., & Schirmer, M. (2002). Randomized double-blind trial of an extract from the pentacyclic alkaloid-chemotype of Uncaria tomentosa for the treatment of rheumatoid arthritisThe Journal of Rheumatology,29(4), 678-681. Full Article

SKIN CANCER

Ciani, F., Tafuri, S.,Troiano, A., Cimmino, A., Fioretto, B. S., Guarino, A. M., ... & Calabrò,V. (2018). Anti-proliferative and pro-apoptotic effects of Uncaria tomentosa aqueous extract in squamous carcinoma cellsJournal of Ethnopharmacology, 211, 285-294. Full Article

THYROID CANCER

Rinner, B., Li, Z. X.,Haas, H., Siegl, V., Sturm, S., Stuppner, H., & Pfragner, R. (2009). Antiproliferative and pro-apoptoticeffects of Uncaria tomentosa in human medullary thyroid carcinoma cellsAnticancer Research,29(11), 4519-4528. Full Article

TUMORS

Santos, K. F.,Gutierres, J. M., Pillat, M. M., Rissi, V. B., dos Santos Araújo, M. D. C.,Bertol, G., ... & Morsch, V. M. (2016). Uncaria tomentosa extract alters the catabolism of adenine nucleotides and expressionof ecto-5′-nucleotidase/CD73 and P2X7 and A1 receptors in the MDA-MB-231cell line. Journal of Ethnopharmacology, 194, 108-116. Full Article

dePaula, L. C. L., Fonseca, F., Perazzo, F., Cruz, F. M., Cubero, D., Trufelli,D. C., ... & del Giglio, A. (2015). Uncaria tomentosa (cat's claw) improves quality of life in patients with advanced solid tumorsThe Journal of Alternative and Complementary Medicine, 21(1), 22-30. Full Article

Dreifuss, A. A., Bastos-Pereira, A. L., Ávila, T. V., da Silva Soley, B., Rivero, A. J.,Aguilar, J. L., & Acco, A. (2010). Antitumoral and antioxidant effects of a hydroalcoholic extract of cat's claw (Uncaria tomentosa) (Willd. Ex Roem. & Schult) in an in vivo carcinosarcoma modelJournal of Ethnopharmacology, 130(1), 127-133. Full Article

Medicinal Properties [peer-reviewed journals]

ANTISEPTIC

S.Bullitta, G. Piluzza, L. Viegi (2007). Plantresources used for traditional ethnoveterinary phytotherapy in Sardinia (Italy).Genet Resour Crop Evol, (54), 1447–1464. Full Article

Medicinal Properties
[other journals]

Medical Conditions [other journals]

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Patient Reports

Dosage Information

Put 1 to 30 drops in 4oz of water and wait one minute before drinking. Start with 1 drop twice daily (30 minutes before meals) increasing slowly up to 30 drops twice daily or as directed by your physician.

Protocols

Safety Information

Product Label

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TEASEL
Teasel: Antiseptic

The diffusion of herbal remedies for therapies on domestic animals in Sardinia (Italy) was investigated by means of expeditions in the regional territory. The monitoring of knowledge related to plant species utilised in the past for traditional veterinary practices, favoured the recovery of ancient local traditions related to veterinary ethnobotany.

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