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Vasoprotective activity of standardized Achillea millefolium extract

Achillea millefolium L. (Asteraceae) is widely used in Europe as a herbal remedy for the treatment of spasms, such as digestive com­plaints. as an emmenagogue. and for irregular menses. Because A. millefolium L. comprises several species, it should be defined more precisely as A. millefolium L. sensu latiore. Several A. millefolium constituents including monoterpenes, sesquiterpenes, flavonoids and caffeolquinic acid derivatives have been reported. Each class of phytoconstituents can at least in part account for specific medicinal properties of A. millefolium.